MetaCyc Pathway: superpathway of purine nucleotide salvage in Shewanella oneidensis MR-1

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Adenosine kinase:
adenosine + ATP→AMP + ADP + H+ (EC 2.7.1.20)
No genes
Purine-nucleoside phosphorylase:
adenosine + phosphate→adenine + α-D-ribose-1-phosphate (EC 2.4.2.1)
SO0092 (deoD-1)
SO1221 (deoD-2)
SO2719 (deoD-3)
SO4297
SO4467
Adenylosuccinate synthase:
IMP + L-aspartate + GTP→adenylosuccinate + GDP + 2 H+ + phosphate (EC 6.3.4.4)
SO1258
SO3937 (purA)
IMP dehydrogenase:
IMP + NAD+ + H2O→XMP + NADH + H+ (EC 1.1.1.205)
SO0805
SO3293 (guaB)
Purine-nucleoside phosphorylase:
guanosine + phosphate→guanine + α-D-ribose-1-phosphate (EC 2.4.2.1; 2.4.2.15)
SO0092 (deoD-1)
SO1221 (deoD-2)
SO2719 (deoD-3)
SO4297
SO4467
Adenine phosphoribosyltransferase (in reverse):
adenine + 5-phospho-α-D-ribose 1-diphosphate→AMP + diphosphate (EC 2.4.2.7)
SO2012 (apt)
Adenylosuccinate lyase:
adenylosuccinate→AMP + fumarate (EC 4.3.2.2)
SO2635 (purB)
GMP synthase (glutamine-hydrolyzing):
XMP + ATP + L-glutamine + H2O→GMP + AMP + L-glutamate + diphosphate + 2 H+ (EC 6.3.5.2)
SO3292 (guaA)
Hypoxanthine phosphoribosyltransferase (in reverse):
guanine + 5-phospho-α-D-ribose 1-diphosphate→GMP + diphosphate (EC 2.4.2.8)
SO0807 (hpt-1)
SO2012 (apt)
SO3803 (hpt-2)
Adenylate kinase:
AMP + ATP→2 ADP (EC 2.7.4.3)
SO2018 (adk)
Guanylate kinase:
GMP + ATP→GDP + ADP (EC 2.7.4.8)
SO0361 (gmk)
Ribonucleoside-diphosphate reductase (in reverse):
ADP + a reduced thioredoxin→dADP + an oxidized thioredoxin + H2O (EC 1.17.4.1)
SO2415 (nrdA)
SO2416 (nrdB)
Nucleoside-diphosphate kinase:
GDP + ATP→GTP + ADP (EC 2.7.4.6)
SO2018 (adk)
SO2274 (ndk)
Nucleoside-diphosphate kinase:
dADP + ATP→ADP + dATP (EC 2.7.4.6)
SO2274 (ndk)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information