MetaCyc Pathway: fatty acid salvage in Shewanella oneidensis MR-1

Butyrate--CoA ligase: decanoate + ATP + coenzyme A→decanoyl-CoA + AMP + diphosphate (EC 6.2.1.2; 6.2.1.3)

SO0075

SO1971

SO2581 (fadD-1)

SO3664 (fadD-2)

decanoyl-CoA + an oxidized electron-transfer flavoprotein + H+→(2E)-dec-2-enoyl-CoA + a reduced electron-transfer flavoprotein (EC 1.3.8.7)

SO2395

SO2536

SO2768

Long-chain-enoyl-CoA hydratase (in reverse): (2E)-dec-2-enoyl-CoA + H2O→(S)-3-hydroxydecanoyl-CoA (EC 4.2.1.74)

SO0021 (fadB)

SO0572

SO3088

SO3908

3-hydroxyacyl-CoA dehydrogenase: (S)-3-hydroxydecanoyl-CoA + NAD+→3-oxodecanoyl-CoA + NADH + H+ (EC 1.1.1.35)

SO0021 (fadB)

SO1680

SO3088

Acetyl-CoA C-acyltransferase (in reverse): 3-oxodecanoyl-CoA + coenzyme A→octanoyl-CoA + acetyl-CoA (EC 2.3.1.16)

SO0020 (fadA)

SO1677 (atoB)

SO3089

octanoyl-CoA + a malonyl-[acp] + H+→a 3-oxodecanoyl-[acp] + CO2 + coenzyme A (EC 2.3.1.207)

SO2901 (fabH-2)

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information