MetaCyc Pathway: tetrapyrrole biosynthesis II (from glycine) in Shewanella oneidensis MR-1

Add experiment(s):


5-aminolevulinate synthase:
glycine + H+ + succinyl-CoA→5-aminolevulinate + CO2 + coenzyme A (EC 2.3.1.37)
No genes
Porphobilinogen synthase:
2 5-aminolevulinate→porphobilinogen + H+ + 2 H2O (EC 4.2.1.24)
SO2587 (hemB-1)
SO4208 (hemB-2)
Hydroxymethylbilane synthase:
4 porphobilinogen + H2O→preuroporphyrinogen + 4 ammonium (EC 2.5.1.61)
SO4313 (hemC)
Uroporphyrinogen-III synthase:
preuroporphyrinogen→uroporphyrinogen-III + H2O (EC 4.2.1.75)
SO4314 (hemD)

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information