MetaCyc Pathway: superpathway of (R,R)-butanediol biosynthesis in Shewanella oneidensis MR-1
| Acetolactate synthase: 2 pyruvate + H+→(S)-2-acetolactate + CO2 (EC 2.2.1.6) |
| SO2278 (ilvH) |
| SO2279 (ilvI) |
| SO3262 (ilvB) |
| SO4346 (ilvM) |
| SO4347 (ilvG) |
| Acetolactate decarboxylase: (S)-2-acetolactate + H+→CO2 + (R)-acetoin (EC 4.1.1.5) |
| No genes |
| (S)-2-acetolactate + an oxidized electron carrier + H+→CO2 + diacetyl + a reduced two electron carrier (spontaneous) |
| No genes |
| diacetyl + NADH + H+→(R)-acetoin + NAD+ (EC 1.1.1.303) |
| No genes |
| (R,R)-butanediol dehydrogenase (in reverse): (R)-acetoin + NADH + H+→(R,R)-2,3-butanediol + NAD+ (EC 1.1.1.4) |
| No genes |
Links:
- Pathway details at MetaCyc
- Fitness data for 5 genes
- All MetaCyc pathways for Shewanella oneidensis MR-1
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information