MetaCyc Pathway: pyruvate decarboxylation to acetyl CoA I in Lysobacter sp. OAE881

a [pyruvate dehydrogenase E2 protein] N⁶-dihydrolipoyl-L-lysine + NAD⁺→a [pyruvate dehydrogenase E2 protein] N⁶-lipoyl-L-lysine + NADH + H⁺ (EC 1.2.1.104; 1.8.1.4)

ABIE51_RS08980

ABIE51_RS18420

a [pyruvate dehydrogenase E2 protein] N⁶-lipoyl-L-lysine + pyruvate + H⁺→a [pyruvate dehydrogenase E2 protein] N⁶-S-acetyldihydrolipoyl-L-lysine + CO₂ (EC 1.2.1.104; 1.2.4.1)

ABIE51_RS04040

ABIE51_RS04045

ABIE51_RS18795

a [pyruvate dehydrogenase E2 protein] N⁶-S-acetyldihydrolipoyl-L-lysine + coenzyme A→a [pyruvate dehydrogenase E2 protein] N⁶-dihydrolipoyl-L-lysine + acetyl-CoA (EC 1.2.1.104; 2.3.1.12)

ABIE51_RS04030

ABIE51_RS18430

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Pathway details at MetaCyc
Fitness data for 7 genes
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All MetaCyc pathways for Lysobacter sp. OAE881

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information