MetaCyc Pathway: Escherichia coli serotype O:127 O antigen biosynthesis in Lysobacter sp. OAE881

Add experiment(s):


UDP-N-acetyl-α-D-glucosamine + di-trans,octa-cis-undecaprenyl phosphate→α-D-GlcNAc-PP-Und + UMP (EC 2.7.8.33)
ABIE51_RS09365
ABIE51_RS12800
α-D-GlcNAc-PP-Und→α-D-GalNAc-PP-Und (EC 5.1.3.26)
No genes
α-D-GalNAc-PP-Und + UDP-N-acetyl-α-D-galactosamine→α-D-GalNAc-(1→3)-α-D-GalNAc-PP-Und + H+ + UDP (EC 2.4.1.306)
No genes
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase:
α-D-GalNAc-(1→3)-α-D-GalNAc-PP-Und + UDP-α-D-galactose→β-D-Gal-(1→3)-α-D-GalNAc-(1→3)-α-D-GalNAc-PP-Und + H+ + UDP (EC 2.4.1.122)
No genes
β-D-Gal-(1→3)-α-D-GalNAc-(1→3)-α-D-GalNAc-PP-Und + GDP-β-L-fucose→α-L-Fuc-(1→2)-β-D-Gal-(1→3)-α-D-GalNAc-(1→3)-α-D-GalNAc-PP-Und + GDP + H+ (EC 2.4.1.308)
No genes
α-L-Fuc-(1→2)-β-D-Gal-(1→3)-α-D-GalNAc-(1→3)-α-D-GalNAc-PP-Und + 2 acetyl-CoA→3,4-diacetyl-α-L-Fuc-(1→2)-β-D-Gal-(1→3)-α-D-GalNAc-(1→3)-α-D-GalNAc-PP-Und + 2 coenzyme A
No genes
3,4-diacetyl-α-L-Fuc-(1→2)-β-D-Gal-(1→3)-α-D-GalNAc-(1→3)-α-D-GalNAc-PP-Und[in] + H+[out]→3,4-diacetyl-α-L-Fuc-(1→2)-β-D-Gal-(1→3)-α-D-GalNAc-(1→3)-α-D-GalNAc-PP-Und[out] + H+[in] (EC 7.5.99.a)
No genes
n 3,4-diacetyl-α-L-Fuc-(1→2)-β-D-Gal-(1→3)-α-D-GalNAc-(1→3)-α-D-GalNAc-PP-Und→Escherichia coli serotype O:127 O antigen + n-1 H+ + n-1 di-trans,octa-cis-undecaprenyl diphosphate (EC 2.4.99.27)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information