MetaCyc Pathway: ureide biosynthesis in Klebsiella michiganensis M5al

IMP dehydrogenase: IMP + NAD+ + H2O→XMP + NADH + H+ (EC 1.1.1.205)

BWI76_RS21030

5'-nucleotidase: XMP + H2O→xanthosine + phosphate (EC 3.1.3.5)

BWI76_RS01930

BWI76_RS03465

BWI76_RS04095

BWI76_RS06865

BWI76_RS20210

BWI76_RS22660

Purine-nucleoside phosphorylase: xanthosine + phosphate→xanthine + α-D-ribose-1-phosphate (EC 2.4.2.1)

BWI76_RS01010

BWI76_RS04145

BWI76_RS06200

BWI76_RS11440

BWI76_RS20605

Xanthine dehydrogenase: xanthine + NAD+ + H2O→urate + NADH + H+ (EC 1.17.1.4)

BWI76_RS17570

BWI76_RS17575

Urate oxidase: urate + dioxygen + H2O→(S)-5-hydroxyisourate + hydrogen peroxide (EC 1.7.3.3)

BWI76_RS10540

Hydroxyisourate hydrolase: (S)-5-hydroxyisourate + H2O→(S)-2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline + H+ (EC 3.5.2.17)

BWI76_RS10515

BWI76_RS17590

(S)-2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline + H+→(S)-(+)-allantoin + CO2 (EC 4.1.1.97)

BWI76_RS10510

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information