MetaCyc Pathway: L-tyrosine degradation I in Klebsiella michiganensis M5al

Add experiment(s):


Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate
(EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
BWI76_RS01925
BWI76_RS03690
BWI76_RS06660
BWI76_RS06750
BWI76_RS07560
BWI76_RS07570
BWI76_RS08675
BWI76_RS09870
BWI76_RS10245
BWI76_RS12985
BWI76_RS13400
BWI76_RS18930
BWI76_RS20205
BWI76_RS22035
BWI76_RS24235
4-hydroxyphenylpyruvate dioxygenase:
3-(4-hydroxyphenyl)pyruvate + dioxygen→homogentisate + CO2
(EC 1.13.11.27)
BWI76_RS04635
BWI76_RS16940
BWI76_RS16945
Homogentisate 1,2-dioxygenase:
homogentisate + dioxygen→4-maleyl-acetoacetate + H+
(EC 1.13.11.5)
No genes
Maleylacetoacetate isomerase:
4-maleyl-acetoacetate→4-fumaryl-acetoacetate
(EC 5.2.1.2)
BWI76_RS19575
Fumarylacetoacetase:
4-fumaryl-acetoacetate + H2O→acetoacetate + fumarate + H+
(EC 3.7.1.2)
BWI76_RS19580

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information