MetaCyc Pathway: L-tyrosine degradation III in Klebsiella michiganensis M5al

Add experiment(s):


Phenylalanine(histidine) transaminase:
L-tyrosine + pyruvate→3-(4-hydroxyphenyl)pyruvate + L-alanine (EC 2.6.1.58)
No genes
Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
BWI76_RS01925
BWI76_RS03690
BWI76_RS06660
BWI76_RS06750
BWI76_RS07560
BWI76_RS07570
BWI76_RS08675
BWI76_RS09870
BWI76_RS10245
BWI76_RS12985
BWI76_RS13400
BWI76_RS18930
BWI76_RS20205
BWI76_RS22035
BWI76_RS24235
4-hydroxyphenylpyruvate decarboxylase:
3-(4-hydroxyphenyl)pyruvate + H+→(4-hydroxyphenyl)acetaldehyde + CO2 (EC 4.1.1.80)
No genes
Alcohol dehydrogenase (in reverse):
(4-hydroxyphenyl)acetaldehyde + NADH + H+→4-tyrosol + NAD+ (EC 1.1.1.1)
BWI76_RS00645
BWI76_RS02835
BWI76_RS03140
BWI76_RS03320
BWI76_RS12395
BWI76_RS13800
BWI76_RS15240
BWI76_RS17250
BWI76_RS25510
BWI76_RS27960

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information