MetaCyc Pathway: fructosyllysine and glucosyllysine metabolism in Klebsiella michiganensis M5al

MetaCyc Pathway: fructosyllysine and glucosyllysine metabolism in Klebsiella michiganensis M5al

aldehydo-D-glucose + L-lysine→N⁶-(1-deoxy-D-fructos-1-yl)-L-lysine + H₂O (spontaneous)

No genes

L-lysine + keto-D-fructose→N⁶-(D-glucosyl)-L-lysine + H₂O (spontaneous)

No genes

N⁶-(1-deoxy-D-fructos-1-yl)-L-lysine_[out] + an [HPr protein]-N^π-phospho-L-histidine_[in]→N⁶-(1-deoxy-6-O-phospho-D-fructos-1-yl)-L-lysine_[in] + an [HPr]-L-histidine_[in]

N⁶-(D-glucosyl)-L-lysine_[out] + an [HPr protein]-N^π-phospho-L-histidine_[in]→N⁶-(6-phospho-D-glucosyl)-L-lysine_[in] + an [HPr]-L-histidine_[in]

N⁶-(1-deoxy-6-O-phospho-D-fructos-1-yl)-L-lysine + H₂O→L-lysine + β-D-glucose 6-phosphate

N⁶-(6-phospho-D-glucosyl)-L-lysine + H₂O→L-lysine + D-fructofuranose 6-phosphate

Links:

Pathway details at MetaCyc
Fitness data for 7 genes
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All MetaCyc pathways for Klebsiella michiganensis M5al

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information