MetaCyc Pathway: L-ascorbate degradation I (bacterial, anaerobic) in Klebsiella michiganensis M5al

MetaCyc Pathway: L-ascorbate degradation I (bacterial, anaerobic) in Klebsiella michiganensis M5al

L-ascorbate_[out] + an [HPr protein]-N^π-phospho-L-histidine_[in]→L-ascorbate 6-phosphate_[in] + an [HPr]-L-histidine_[in] (EC 2.7.1.194)

L-ascorbate 6-phosphate + H₂O→3-dehydro-L-gulonate 6-phosphate

3-dehydro-L-gulonate-6-phosphate decarboxylase:
3-dehydro-L-gulonate 6-phosphate + H⁺→L-xylulose 5-phosphate + CO₂ (EC 4.1.1.85)

L-ribulose-5-phosphate 3-epimerase (in reverse):
L-xylulose 5-phosphate→L-ribulose 5-phosphate (EC 5.1.3.22)

L-ribulose-5-phosphate 4-epimerase:
L-ribulose 5-phosphate→D-xylulose 5-phosphate (EC 5.1.3.4)

Links:

Pathway details at MetaCyc
Fitness data for 14 genes
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All MetaCyc pathways for Klebsiella michiganensis M5al

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information