MetaCyc Pathway: guanosine ribonucleotides de novo biosynthesis in Klebsiella michiganensis M5al

Add experiment(s):


IMP dehydrogenase:
IMP + NAD+ + H2O→XMP + NADH + H+ (EC 1.1.1.205)
BWI76_RS21030
GMP synthase (glutamine-hydrolyzing):
XMP + ATP + L-glutamine + H2O→GMP + AMP + L-glutamate + diphosphate + 2 H+ (EC 6.3.5.2)
BWI76_RS14000
BWI76_RS21025
Guanylate kinase:
GMP + ATP→GDP + ADP (EC 2.7.4.8)
BWI76_RS02190
BWI76_RS27420
Nucleoside-diphosphate kinase:
GDP + ATP→GTP + ADP (EC 2.7.4.6)
BWI76_RS06840
BWI76_RS21100

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information