MetaCyc Pathway: chorismate biosynthesis from 3-dehydroquinate in Klebsiella michiganensis M5al

Add experiment(s):


3-dehydroquinate dehydratase:
3-dehydroquinate→3-dehydroshikimate + H2O
(EC 4.2.1.10)
BWI76_RS04645
BWI76_RS22790
Shikimate dehydrogenase (in reverse):
3-dehydroshikimate + NADPH + H+→shikimate + NADP+
(EC 1.1.1.25)
BWI76_RS01715
BWI76_RS04655
BWI76_RS06460
BWI76_RS16935
BWI76_RS25645
Shikimate kinase:
shikimate + ATP→shikimate 3-phosphate + ADP + H+
(EC 2.7.1.71)
BWI76_RS06185
BWI76_RS26090
3-phosphoshikimate 1-carboxyvinyltransferase:
shikimate 3-phosphate + phosphoenolpyruvate→5-enolpyruvoyl-shikimate 3-phosphate + phosphate
(EC 2.5.1.19)
BWI76_RS09760
Chorismate synthase:
5-enolpyruvoyl-shikimate 3-phosphate→chorismate + phosphate
(EC 4.2.3.5)
BWI76_RS20435

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information