MetaCyc Pathway: partial TCA cycle (obligate autotrophs) in Klebsiella michiganensis M5al

Phosphoenolpyruvate carboxylase (in reverse): phosphoenolpyruvate + hydrogen carbonate→oxaloacetate + phosphate (EC 4.1.1.31)

BWI76_RS00835

Citrate (Si)-synthase: oxaloacetate + acetyl-CoA + H2O→citrate + coenzyme A + H+ (EC 2.3.3.1; 2.3.3.16; 2.3.3.3)

BWI76_RS08385

BWI76_RS19140

oxaloacetate[in] + an electron-transfer quinol→(S)-malate[in] + an electron-transfer quinone (EC 1.1.5.4)

BWI76_RS16065

BWI76_RS19870

Aconitate hydratase: citrate→cis-aconitate + H2O (EC 4.2.1.3)

BWI76_RS04910

BWI76_RS11940

Fumarate hydratase: (S)-malate→fumarate + H2O (EC 4.2.1.2)

BWI76_RS08450

BWI76_RS16115

BWI76_RS16270

BWI76_RS16275

BWI76_RS16955

Aconitate hydratase: cis-aconitate + H2O→D-threo-isocitrate (EC 4.2.1.3)

BWI76_RS04910

BWI76_RS11940

Succinate dehydrogenase (ubiquinone) (in reverse): fumarate[in] + an electron-transfer quinol→succinate[in] + an electron-transfer quinone (EC 1.3.5.1)

No genes

Isocitrate dehydrogenase (NADP(+)): D-threo-isocitrate + NADP+→2-oxoglutarate + CO2 + NADPH (EC 1.1.1.42)

BWI76_RS11330

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information