MetaCyc Pathway: L-threonine degradation I in Klebsiella michiganensis M5al

Add experiment(s):


Threonine ammonia-lyase:
L-threonine→(Z)-2-aminobutenoate + H2O
(EC 4.3.1.19)
BWI76_RS00980
1-aminocyclopropane-1-carboxylate deaminase:
(Z)-2-aminobutenoate→2-iminobutanoate
(spontaneous) (EC 3.5.99.7; 4.3.1.19; 4.4.1.1; 4.4.1.11; 4.4.1.2)
BWI76_RS00980
BWI76_RS16730
BWI76_RS24210
2-iminobutanoate + H2O→2-oxobutanoate + ammonium (spontaneous) (EC 3.5.99.10; 3.5.99.7; 4.3.1.19; 4.4.1.1; 4.4.1.11; 4.4.1.2)
BWI76_RS00980
BWI76_RS02985
BWI76_RS16730
BWI76_RS24210
Formate C-acetyltransferase (in reverse):
2-oxobutanoate + coenzyme A→propanoyl-CoA + formate
(EC 2.3.1.54)
BWI76_RS03575
BWI76_RS09070
BWI76_RS09735
BWI76_RS10660
BWI76_RS21375
propanoyl-CoA + phosphate→propanoyl phosphate + coenzyme A (EC 2.3.1.222)
BWI76_RS03560
BWI76_RS20240
BWI76_RS23150
Acetate kinase (in reverse):
propanoyl phosphate + ADP→propanoate + ATP
(EC 2.7.2.1; 2.7.2.14; 2.7.2.15; 2.7.2.7)
BWI76_RS20235
BWI76_RS23200

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information