MetaCyc Pathway: formaldehyde assimilation II (assimilatory RuMP Cycle) in Klebsiella michiganensis M5al

MetaCyc Pathway: formaldehyde assimilation II (assimilatory RuMP Cycle) in Klebsiella michiganensis M5al

6-phosphofructokinase:
β-D-fructofuranose 6-phosphate + ATP→β-D-fructofuranose 1,6-bisphosphate + ADP + H⁺ (EC 2.7.1.11)

3-hexulose-6-phosphate synthase (in reverse):
formaldehyde + D-ribulose 5-phosphate→hexulose 6-phosphate (EC 4.1.2.43)

No genes

Fructose-bisphosphate aldolase:
β-D-fructofuranose 1,6-bisphosphate→glycerone phosphate + D-glyceraldehyde 3-phosphate (EC 4.1.2.13)

6-phospho-3-hexuloisomerase:
hexulose 6-phosphate→β-D-fructofuranose 6-phosphate (EC 5.3.1.27)

No genes

Transketolase (in reverse):
β-D-fructofuranose 6-phosphate + D-glyceraldehyde 3-phosphate→D-erythrose 4-phosphate + D-xylulose 5-phosphate (EC 2.2.1.1)

Transaldolase (in reverse):
D-erythrose 4-phosphate + β-D-fructofuranose 6-phosphate→D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate (EC 2.2.1.2)

Transketolase:
D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate→D-xylulose 5-phosphate + D-ribose 5-phosphate (EC 2.2.1.1)

Ribose-5-phosphate isomerase:
D-ribose 5-phosphate→D-ribulose 5-phosphate (EC 5.3.1.6)

Ribulose-phosphate 3-epimerase (in reverse):
D-xylulose 5-phosphate→D-ribulose 5-phosphate (EC 5.1.3.1)

Links:

Pathway details at MetaCyc
Fitness data for 25 genes
Select organism:
All MetaCyc pathways for Klebsiella michiganensis M5al

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information