MetaCyc Pathway: L-tyrosine degradation I in Herbaspirillum seropedicae SmR1

Aspartate transaminase: L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)

HSERO_RS05425

HSERO_RS08395

HSERO_RS08705

HSERO_RS09025

HSERO_RS10455

HSERO_RS12210

HSERO_RS14160

HSERO_RS15115

HSERO_RS15220

HSERO_RS15835

HSERO_RS17885

HSERO_RS20335

HSERO_RS22025

HSERO_RS23235

HSERO_RS23520

4-hydroxyphenylpyruvate dioxygenase: 3-(4-hydroxyphenyl)pyruvate + dioxygen→homogentisate + CO2 (EC 1.13.11.27)

HSERO_RS08335

HSERO_RS18790

HSERO_RS18800

Homogentisate 1,2-dioxygenase: homogentisate + dioxygen→4-maleyl-acetoacetate + H+ (EC 1.13.11.5)

HSERO_RS05605

Maleylacetoacetate isomerase: 4-maleyl-acetoacetate→4-fumaryl-acetoacetate (EC 5.2.1.2)

HSERO_RS05615

Fumarylacetoacetase: 4-fumaryl-acetoacetate + H2O→acetoacetate + fumarate + H+ (EC 3.7.1.2)

HSERO_RS05610

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information