MetaCyc Pathway: polyhydroxybutanoate biosynthesis in Herbaspirillum seropedicae SmR1

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Acetyl-CoA C-acyltransferase:
2 acetyl-CoA→acetoacetyl-CoA + coenzyme A
(EC 2.3.1.16; 2.3.1.9)
HSERO_RS01180
HSERO_RS01265
HSERO_RS04635
HSERO_RS19070
HSERO_RS19990
HSERO_RS20030
HSERO_RS20660
Acetoacetyl-CoA reductase (in reverse):
acetoacetyl-CoA + NADPH + H+→(3R)-3-hydroxybutanoyl-CoA + NADP+
(EC 1.1.1.36)
HSERO_RS15035
(3R)-3-hydroxybutanoyl-CoA + poly-[(R)-3-hydroxybutanoate]→poly-[(R)-3-hydroxybutanoate] + coenzyme A (EC 2.3.1.304)
HSERO_RS15040

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information