MetaCyc Pathway: L-valine biosynthesis in Enterobacter sp. TBS_079

Add experiment(s):


Acetolactate synthase:
2 pyruvate + H+→(S)-2-acetolactate + CO2
(EC 2.2.1.6)
MPMX20_00031
MPMX20_00032
MPMX20_00771
MPMX20_00772
MPMX20_01224
MPMX20_03783
MPMX20_04501
MPMX20_04502
Ketol-acid reductoisomerase (in reverse):
(S)-2-acetolactate + NADPH + H+→(2R)-2,3-dihydroxy-3-methylbutanoate + NADP+
(EC 1.1.1.86)
MPMX20_04496
Dihydroxy-acid dehydratase:
(2R)-2,3-dihydroxy-3-methylbutanoate→3-methyl-2-oxobutanoate + H2O
(EC 4.2.1.9)
MPMX20_00552
MPMX20_04499
Branched-chain-amino-acid transaminase (in reverse):
3-methyl-2-oxobutanoate + L-glutamate→L-valine + 2-oxoglutarate
(EC 2.6.1.42)
MPMX20_04500

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information