MetaCyc Pathway: pyrimidine deoxyribonucleotides de novo biosynthesis I in Enterobacter sp. TBS_079

Nucleoside-triphosphatase: CTP + H2O→CDP + H+ + phosphate (EC 3.6.1.15; 3.6.1.5)

MPMX20_03812

Ribonucleoside-diphosphate reductase (in reverse): UDP + a reduced thioredoxin→dUDP + an oxidized thioredoxin + H2O (EC 1.17.4.1)

MPMX20_03181

MPMX20_03182

MPMX20_03555

MPMX20_03556

MPMX20_03557

Ribonucleoside-diphosphate reductase (in reverse): CDP + a reduced thioredoxin→dCDP + an oxidized thioredoxin + H2O (EC 1.17.4.1)

MPMX20_03181

MPMX20_03182

MPMX20_03555

MPMX20_03556

MPMX20_03557

Nucleoside-diphosphate kinase: dUDP + ATP→dUTP + ADP (EC 2.7.4.6)

MPMX20_03396

Nucleoside-diphosphate kinase: dCDP + ATP→dCTP + ADP (EC 2.7.4.6)

MPMX20_01076

MPMX20_03396

dUTP diphosphatase: dUTP + H2O→dUMP + diphosphate + H+ (EC 3.6.1.23; 3.6.1.9)

MPMX20_00095

MPMX20_03526

Thymidylate synthase: dUMP + a 5,10-methylenetetrahydrofolate→dTMP + a 7,8-dihydrofolate (EC 2.1.1.45)

MPMX20_03690

T(2)-induced deoxynucleotide kinase: dTMP + ATP→dTDP + ADP (EC 2.7.4.12; 2.7.4.13; 2.7.4.9)

MPMX20_01778

Nucleoside-diphosphate kinase: dTDP + ATP→dTTP + ADP (EC 2.7.4.6)

MPMX20_01076

MPMX20_03396

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information