MetaCyc Pathway: molybdopterin biosynthesis in Enterobacter sp. TBS_079

ATP + a small subunit of molybdopterin synthase + H+→a carboxy-adenylated [small subunit of molybdopterin synthase] + diphosphate (EC 2.7.7.80)

MPMX20_01466

Cysteine desulfurase: L-cysteine + a [molybdopterin synthase sulfurtransferase]-L-cysteine→a [molybdopterin synthase sulfurtransferase]-S-sulfanyl-L-cysteine + L-alanine (EC 2.8.1.7)

MPMX20_01947

MPMX20_03411

MPMX20_03673

MPMX20_03674

GTP + a reduced two electron carrier + S-adenosyl-L-methionine→(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate + an oxidized electron carrier + 5'-deoxyadenosine + L-methionine + H+ (EC 4.1.99.22)

MPMX20_01410

a carboxy-adenylated [small subunit of molybdopterin synthase] + a [molybdopterin synthase sulfurtransferase]-S-sulfanyl-L-cysteine + a reduced two electron carrier→a thiocarboxylated [small subunit of molybdopterin synthase] + AMP + an oxidized electron carrier + a [molybdopterin synthase sulfurtransferase]-L-cysteine + H+ (EC 2.8.1.11)

MPMX20_01859

(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate→cyclic pyranopterin phosphate + diphosphate (EC 4.6.1.17)

MPMX20_01412

cyclic pyranopterin phosphate + 2 a thiocarboxylated [small subunit of molybdopterin synthase] + H2O→molybdopterin + 2 a small subunit of molybdopterin synthase + 4 H+ (EC 2.8.1.12)

MPMX20_01413

MPMX20_01414

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information