MetaCyc Pathway: ureide biosynthesis in Escherichia coli Nissle 1917

Add experiment(s):


IMP dehydrogenase:
IMP + NAD+ + H2O→XMP + NADH + H+ (EC 1.1.1.205)
ECOLIN_RS14240
5'-nucleotidase:
XMP + H2O→xanthosine + phosphate (EC 3.1.3.5)
ECOLIN_RS02845
ECOLIN_RS13300
ECOLIN_RS15345
ECOLIN_RS22740
ECOLIN_RS22745
ECOLIN_RS22755
ECOLIN_RS23470
ECOLIN_RS25105
Purine-nucleoside phosphorylase:
xanthosine + phosphate→xanthine + α-D-ribose-1-phosphate (EC 2.4.2.1)
ECOLIN_RS02375
ECOLIN_RS13830
ECOLIN_RS25165
Xanthine dehydrogenase:
xanthine + NAD+ + H2O→urate + NADH + H+ (EC 1.17.1.4)
ECOLIN_RS15980
ECOLIN_RS15985
ECOLIN_RS15990
Urate oxidase:
urate + dioxygen + H2O→(S)-5-hydroxyisourate + hydrogen peroxide (EC 1.7.3.3)
No genes
Hydroxyisourate hydrolase:
(S)-5-hydroxyisourate + H2O→(S)-2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline + H+ (EC 3.5.2.17)
ECOLIN_RS11195
(S)-2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline + H+→(S)-(+)-allantoin + CO2 (EC 4.1.1.97)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information