MetaCyc Pathway: superpathway of glycol metabolism and degradation in Escherichia coli Nissle 1917

Lactaldehyde reductase: ethylene glycol + NAD+→glycolaldehyde + NADH + H+ (EC 1.1.1.77)

ECOLIN_RS15605

Glycolaldehyde dehydrogenase: glycolaldehyde + NAD+ + H2O→glycolate + NADH + 2 H+ (EC 1.2.1.21)

ECOLIN_RS08190

Glycolate dehydrogenase: glycolate[in] + an electron-transfer quinone→glyoxylate[in] + an electron-transfer quinol (EC 1.1.99.14)

ECOLIN_RS09430

ECOLIN_RS17130

ECOLIN_RS17135

ECOLIN_RS17140

Tartronate-semialdehyde synthase: 2 glyoxylate + H+→(2R)-tartronate semialdehyde + CO2 (EC 4.1.1.47)

ECOLIN_RS02955

Malate synthase: glyoxylate + acetyl-CoA + H2O→(S)-malate + coenzyme A + H+ (EC 2.3.3.9)

ECOLIN_RS17120

ECOLIN_RS23140

ECOLIN_RS25425

ECOLIN_RS25510

ECOLIN_RS26875

2-hydroxy-3-oxopropionate reductase (in reverse): (2R)-tartronate semialdehyde + NAD(P)H + H+→D-glycerate + NAD(P)+ (EC 1.1.1.60)

ECOLIN_RS02965

ECOLIN_RS17960

D-glycerate + ATP→2-phospho-D-glycerate + ADP + H+ (EC 2.7.1.165)

ECOLIN_RS02985

ECOLIN_RS17955

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information