MetaCyc Pathway: glutathione biosynthesis in Escherichia coli Nissle 1917

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Glutamate--cysteine ligase:
L-cysteine + L-glutamate + ATP→γ-L-glutamyl-L-cysteine + ADP + H+ + phosphate (EC 6.3.2.2)
ECOLIN_RS03175
ECOLIN_RS14990
Glutathione synthase:
γ-L-glutamyl-L-cysteine + ATP + glycine→glutathione + ADP + H+ + phosphate (EC 6.3.2.3)
ECOLIN_RS16395

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information