MetaCyc Pathway: superpathway of fucose and rhamnose degradation in Escherichia coli Nissle 1917

Add experiment(s):


β-L-fucopyranose→α-L-fucopyranose (spontaneous) (EC 5.1.3.29)
ECOLIN_RS15630
α-L-rhamnopyranose→β-L-rhamnopyranose (EC 5.1.3.32)
ECOLIN_RS22475
L-fucose isomerase:
α-L-fucopyranose→L-fuculose (EC 5.3.1.25)
ECOLIN_RS15620
L-rhamnose isomerase:
β-L-rhamnopyranose→keto-L-rhamnulose (EC 5.3.1.14)
ECOLIN_RS22485
L-fuculokinase:
L-fuculose + ATP→L-fuculose 1-phosphate + ADP + H+ (EC 2.7.1.51)
ECOLIN_RS15625
keto-L-rhamnulose→L-rhamnulofuranose (spontaneous)
No genes
L-fuculose-phosphate aldolase:
L-fuculose 1-phosphate→(S)-lactaldehyde + glycerone phosphate (EC 4.1.2.17)
ECOLIN_RS15610
ECOLIN_RS26995
Rhamnulokinase:
L-rhamnulofuranose + ATP→L-rhamnulose 1-phosphate + ADP + H+ (EC 2.7.1.5)
ECOLIN_RS22490
Rhamnulose-1-phosphate aldolase:
L-rhamnulose 1-phosphate→(S)-lactaldehyde + glycerone phosphate (EC 4.1.2.19)
ECOLIN_RS22480
Lactaldehyde dehydrogenase:
(S)-lactaldehyde + NAD+ + H2O→(S)-lactate + NADH + 2 H+ (EC 1.2.1.22)
ECOLIN_RS08190
Lactaldehyde reductase (in reverse):
(S)-lactaldehyde + NADH + H+→(S)-propane-1,2-diol + NAD+ (EC 1.1.1.77)
ECOLIN_RS15605
(S)-lactate[in] + an electron-transfer quinone→pyruvate[in] + an electron-transfer quinol (EC 1.1.5.M6)
ECOLIN_RS20580

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information