MetaCyc Pathway: L-tyrosine degradation I in Dyella japonica UNC79MFTsu3.2

Add experiment(s):


Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
ABZR86_RS01145
ABZR86_RS02120
ABZR86_RS03710
ABZR86_RS04055
ABZR86_RS06725
ABZR86_RS08550
ABZR86_RS11705
ABZR86_RS12435
ABZR86_RS14075
ABZR86_RS16490
ABZR86_RS17110
ABZR86_RS20415
4-hydroxyphenylpyruvate dioxygenase:
3-(4-hydroxyphenyl)pyruvate + dioxygen→homogentisate + CO2 (EC 1.13.11.27)
ABZR86_RS18470
Homogentisate 1,2-dioxygenase:
homogentisate + dioxygen→4-maleyl-acetoacetate + H+ (EC 1.13.11.5)
ABZR86_RS18480
Maleylacetoacetate isomerase:
4-maleyl-acetoacetate→4-fumaryl-acetoacetate (EC 5.2.1.2)
ABZR86_RS00140
ABZR86_RS18680
Fumarylacetoacetase:
4-fumaryl-acetoacetate + H2O→acetoacetate + fumarate + H+ (EC 3.7.1.2)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information