MetaCyc Pathway: guanosine ribonucleotides de novo biosynthesis in Dyella japonica UNC79MFTsu3.2

Add experiment(s):


IMP dehydrogenase:
IMP + NAD+ + H2O→XMP + NADH + H+
(EC 1.1.1.205)
ABZR86_RS04320
ABZR86_RS04410
ABZR86_RS05410
ABZR86_RS18910
GMP synthase (glutamine-hydrolyzing):
XMP + ATP + L-glutamine + H2O→GMP + AMP + L-glutamate + diphosphate + 2 H+
(EC 6.3.5.2)
ABZR86_RS05405
ABZR86_RS15465
ABZR86_RS15715
Guanylate kinase:
GMP + ATP→GDP + ADP
(EC 2.7.4.8)
ABZR86_RS11890
Nucleoside-diphosphate kinase:
GDP + ATP→GTP + ADP
(EC 2.7.4.6)
ABZR86_RS05460

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information