MetaCyc Pathway: glycine cleavage in Caulobacter crescentus NA1000

a [glycine-cleavage complex H protein] N⁶-[(R)-lipoyl]-L-lysine + glycine + H⁺→a [glycine-cleavage complex H protein] N⁶-aminomethyldihydrolipoyl-L-lysine + CO₂ (EC 1.4.1.27; 1.4.4.2)

CCNA_03462

CCNA_03463

a [glycine-cleavage complex H protein] N⁶-aminomethyldihydrolipoyl-L-lysine + a tetrahydrofolate→a [glycine-cleavage complex H protein] N⁶-dihydrolipoyl-L-lysine + ammonium + a 5,10-methylenetetrahydrofolate (EC 1.4.1.27; 2.1.2.10)

a [glycine-cleavage complex H protein] N⁶-dihydrolipoyl-L-lysine + NAD⁺→a [glycine-cleavage complex H protein] N⁶-[(R)-lipoyl]-L-lysine + NADH + H⁺ (EC 1.4.1.27; 1.8.1.4)

CCNA_00346

CCNA_01805

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Pathway details at MetaCyc
Fitness data for 8 genes
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All MetaCyc pathways for Caulobacter crescentus NA1000

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information