MetaCyc Pathway: L-tyrosine degradation I in Ralstonia sp. UNC404CL21Col

Add experiment(s):


Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate
(EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
ABZR87_RS02495
ABZR87_RS03260
ABZR87_RS04630
ABZR87_RS05850
ABZR87_RS05985
ABZR87_RS05990
ABZR87_RS08250
ABZR87_RS08830
ABZR87_RS08860
ABZR87_RS09455
ABZR87_RS09835
ABZR87_RS09935
ABZR87_RS11440
ABZR87_RS14645
ABZR87_RS17005
ABZR87_RS18535
ABZR87_RS19655
ABZR87_RS21785
4-hydroxyphenylpyruvate dioxygenase:
3-(4-hydroxyphenyl)pyruvate + dioxygen→homogentisate + CO2
(EC 1.13.11.27)
ABZR87_RS03395
ABZR87_RS19800
ABZR87_RS19825
ABZR87_RS22710
Homogentisate 1,2-dioxygenase:
homogentisate + dioxygen→4-maleyl-acetoacetate + H+
(EC 1.13.11.5)
ABZR87_RS20850
Maleylacetoacetate isomerase:
4-maleyl-acetoacetate→4-fumaryl-acetoacetate
(EC 5.2.1.2)
ABZR87_RS06920
Fumarylacetoacetase:
4-fumaryl-acetoacetate + H2O→acetoacetate + fumarate + H+
(EC 3.7.1.2)
ABZR87_RS06915
ABZR87_RS20855

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information