MetaCyc Pathway: superpathway of sulfate assimilation and cysteine biosynthesis in Ralstonia sp. UNC404CL21Col

Add experiment(s):


Phosphoglycerate dehydrogenase:
3-phospho-D-glycerate + NAD+→3-phosphooxypyruvate + NADH + H+
(EC 1.1.1.95)
ABZR87_RS05285
ABZR87_RS05875
ABZR87_RS06255
ABZR87_RS17535
ABZR87_RS19060
ABZR87_RS21550
ABZR87_RS21670
Sulfate adenylyltransferase:
sulfate + ATP + H+→adenosine 5'-phosphosulfate + diphosphate
(EC 2.7.7.4)
ABZR87_RS00190
ABZR87_RS00195
Adenylyl-sulfate kinase:
adenosine 5'-phosphosulfate + ATP→3'-phosphoadenylyl-sulfate + ADP + H+
(EC 2.7.1.25)
ABZR87_RS16415
Phosphoserine transaminase (in reverse):
3-phosphooxypyruvate + L-glutamateO-phospho-L-serine + 2-oxoglutarate
(EC 2.6.1.52)
ABZR87_RS09445
Phosphoadenylyl-sulfate reductase (thioredoxin) (in reverse):
3'-phosphoadenylyl-sulfate + a reduced thioredoxin→sulfite + adenosine 3',5'-bisphosphate + an oxidized thioredoxin + 2 H+
(EC 1.8.4.8)
ABZR87_RS00200
Phosphoserine phosphatase:
O-phospho-L-serine + H2O→L-serine + phosphate
(EC 3.1.3.3)
ABZR87_RS00930
ABZR87_RS13250
ABZR87_RS20450
Serine O-acetyltransferase:
L-serine + acetyl-CoAO-acetyl-L-serine + coenzyme A
(EC 2.3.1.30)
ABZR87_RS10620
ABZR87_RS21775
Sulfite reductase (NADPH) (in reverse):
sulfite + 3 NADPH + 5 H+→hydrogen sulfide + 3 NADP+ + 3 H2O
(EC 1.8.1.2)
ABZR87_RS00210
ABZR87_RS19620
Cysteine synthase:
O-acetyl-L-serine + hydrogen sulfide→L-cysteine + acetate + H+
(EC 2.5.1.47)
ABZR87_RS09515

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information