MetaCyc Pathway: 8-amino-7-oxononanoate biosynthesis IV in Ralstonia sp. UNC404CL21Col

glutaryl-CoA + a malonyl-[acp] + H+→a 3-oxopimeloyl-[acp] + CO2 + coenzyme A

ABZR87_RS10135

3-oxoacyl-[acyl-carrier-protein] reductase (in reverse): a 3-oxopimeloyl-[acp] + NADPH + H+→a (3R)-3-hydroxypimeloyl-[acp] + NADP+ (EC 1.1.1.100)

ABZR87_RS01455

ABZR87_RS03540

ABZR87_RS03590

ABZR87_RS07820

ABZR87_RS08385

ABZR87_RS10145

ABZR87_RS12060

ABZR87_RS12565

ABZR87_RS15380

ABZR87_RS16115

ABZR87_RS17625

ABZR87_RS17640

ABZR87_RS20660

ABZR87_RS20680

ABZR87_RS22225

ABZR87_RS22525

3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase: a (3R)-3-hydroxypimeloyl-[acp]→a 2-enoyl-pimeloyl-[acp] + H2O (EC 4.2.1.59)

ABZR87_RS11880

Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse): a 2-enoyl-pimeloyl-[acp] + NADH + H+→a pimeloyl-[acp] + NAD+ (EC 1.3.1.9)

ABZR87_RS10675

ABZR87_RS22515

8-amino-7-oxononanoate synthase: a pimeloyl-[acp] + L-alanine + H+→(8S)-8-amino-7-oxononanoate + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.47)

ABZR87_RS12340

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information