MetaCyc Pathway: L-tryptophan degradation XIII (reductive Stickland reaction) in Ralstonia sp. UNC404CL21Col

Add experiment(s):


Aspartate transaminase:
L-tryptophan + 2-oxoglutarate→(indol-3-yl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27)
ABZR87_RS04630
ABZR87_RS05850
ABZR87_RS05990
ABZR87_RS08250
ABZR87_RS08830
ABZR87_RS08860
ABZR87_RS09835
ABZR87_RS11440
ABZR87_RS14645
ABZR87_RS17005
ABZR87_RS18535
ABZR87_RS19655
ABZR87_RS21785
Indolelactate dehydrogenase (in reverse):
(indol-3-yl)pyruvate + NADH + H+→(R)-3-(indol-3-yl)lactate + NAD+ (EC 1.1.1.110)
No genes
Cinnamoyl-CoA:phenyllactate CoA-transferase:
(R)-3-(indol-3-yl)lactate + 3-(indol-3-yl)acryloyl-CoA→3-(indol-3-yl)acrylate + (R)-3-(indol-3-yl)lactoyl-CoA (EC 2.8.3.17)
No genes
3-(indol-3-yl)acrylate + a reduced electron-transfer flavoprotein→3-(1H-indol-3-yl)propanoate + an oxidized electron-transfer flavoprotein + H+ (EC 1.3.8.15)
No genes
(R)-3-(indol-3-yl)lactoyl-CoA→3-(indol-3-yl)acryloyl-CoA + H2O (EC 4.2.1.175)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information