MetaCyc Pathway: superpathway of anaerobic energy metabolism (invertebrates) in Ralstonia sp. UNC404CL21Col

Add experiment(s):


Phosphoenolpyruvate carboxykinase (GTP) (in reverse):
phosphoenolpyruvate + CO2 + GDP→oxaloacetate + GTP (EC 4.1.1.32)
ABZR87_RS05280
Pyruvate kinase (in reverse):
phosphoenolpyruvate + ADP + H+→pyruvate + ATP (EC 2.7.1.40)
ABZR87_RS03905
ABZR87_RS08070
Phosphoenolpyruvate carboxykinase (GTP) (in reverse):
phosphoenolpyruvate + CO2 + IDP→oxaloacetate + ITP (EC 4.1.1.32)
ABZR87_RS05280
Alanine transaminase (in reverse):
pyruvate + L-glutamate→2-oxoglutarate + L-alanine (EC 2.6.1.2)
ABZR87_RS11440
Malate dehydrogenase (in reverse):
oxaloacetate + NADH + H+→(S)-malate + NAD+ (EC 1.1.1.37; 1.1.1.38)
ABZR87_RS14580
Malate dehydrogenase (oxaloacetate-decarboxylating):
(S)-malate + NAD+→pyruvate + CO2 + NADH (EC 1.1.1.38)
No genes
Alanine racemase:
L-alanine→D-alanine (EC 5.1.1.1; 5.1.1.10)
ABZR87_RS11665
Aspartate transaminase:
2-oxoglutarate + L-aspartate→L-glutamate + oxaloacetate (EC 2.6.1.1)
ABZR87_RS04630
ABZR87_RS05850
ABZR87_RS05990
ABZR87_RS08250
ABZR87_RS08830
ABZR87_RS08860
ABZR87_RS09835
ABZR87_RS11440
ABZR87_RS14645
ABZR87_RS17005
ABZR87_RS18535
ABZR87_RS19655
ABZR87_RS21785
Fumarate hydratase:
(S)-malate→fumarate + H2O (EC 4.2.1.2)
ABZR87_RS14375
ABZR87_RS18630
pyruvate + coenzyme A + NAD+→CO2 + acetyl-CoA + NADH (EC 1.2.1.104)
ABZR87_RS13465
ABZR87_RS13470
Succinate dehydrogenase (ubiquinone) (in reverse):
fumarate[in] + a rhodoquinol→succinate[in] + a rhodoquinone (EC 1.3.5.1)
No genes
acetyl-CoA + succinate→acetate + succinyl-CoA (EC 2.8.3.18)
No genes
succinate + propanoyl-CoA→succinyl-CoA + propanoate (EC 2.8.3.27)
No genes
Methylmalonyl-CoA mutase (in reverse):
succinyl-CoA→(R)-methylmalonyl-CoA (EC 5.4.99.2)
ABZR87_RS06050
Succinate--CoA ligase (ADP-forming) (in reverse):
succinyl-CoA + ADP + phosphate→succinate + ATP + coenzyme A (EC 6.2.1.5)
ABZR87_RS07980
ABZR87_RS07985
Methylmalonyl-CoA epimerase:
(R)-methylmalonyl-CoA→(S)-methylmalonyl-CoA (EC 5.1.99.1)
No genes
Propionyl-CoA carboxylase (in reverse):
(S)-methylmalonyl-CoA + ADP + H+ + phosphate→propanoyl-CoA + ATP + hydrogen carbonate (EC 6.4.1.3)
ABZR87_RS10655
ABZR87_RS14485

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information