MetaCyc Pathway: pyruvate fermentation to butanol II (engineered) in Ralstonia sp. UNC404CL21Col

Add experiment(s):


Acetyl-CoA C-acyltransferase:
2 acetyl-CoA→acetoacetyl-CoA + coenzyme A (EC 2.3.1.16; 2.3.1.9)
ABZR87_RS06305
ABZR87_RS07485
ABZR87_RS07810
ABZR87_RS12575
ABZR87_RS13270
ABZR87_RS13295
ABZR87_RS15790
ABZR87_RS23340
3-hydroxyacyl-CoA dehydrogenase (in reverse):
acetoacetyl-CoA + NADH + H+→(S)-3-hydroxybutanoyl-CoA + NAD+ (EC 1.1.1.35)
ABZR87_RS00745
ABZR87_RS06125
ABZR87_RS07480
ABZR87_RS12585
ABZR87_RS14655
ABZR87_RS23345
(S)-3-hydroxybutanoyl-CoA→crotonyl-CoA + H2O (EC 4.2.1.150)
ABZR87_RS06190
ABZR87_RS06470
ABZR87_RS07480
ABZR87_RS07495
ABZR87_RS11295
ABZR87_RS12585
ABZR87_RS14660
ABZR87_RS16545
ABZR87_RS16935
ABZR87_RS20900
ABZR87_RS21810
Trans-2-enoyl-CoA reductase (NAD(+)) (in reverse):
crotonyl-CoA + NADH + H+→butanoyl-CoA + NAD+ (EC 1.3.1.44)
ABZR87_RS06200
ABZR87_RS07825
ABZR87_RS16550
ABZR87_RS17460
ABZR87_RS20395
ABZR87_RS20865
ABZR87_RS23335
Butanal dehydrogenase (in reverse):
butanoyl-CoA + NAD(P)H + H+→1-butanal + coenzyme A + NAD(P)+ (EC 1.2.1.57)
No genes
1-butanal + NADH + H+→butan-1-ol + NAD+
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information