MetaCyc Pathway: superpathway of glyoxylate cycle and fatty acid degradation in Ralstonia sp. UNC404CL21Col

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a 2,3,4-saturated fatty acid + ATP + coenzyme A→a 2,3,4-saturated fatty acyl CoA + AMP + diphosphate
No genes
Acyl-CoA oxidase:
a 2,3,4-saturated fatty acyl CoA + dioxygen→a (2E)-2-enoyl-CoA + hydrogen peroxide
(EC 1.3.3.6)
No genes
Enoyl-CoA hydratase (in reverse):
a (2E)-2-enoyl-CoA + H2O→a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA
(EC 4.2.1.17)
ABZR87_RS02095
ABZR87_RS02100
ABZR87_RS06190
ABZR87_RS06470
ABZR87_RS07480
ABZR87_RS07495
ABZR87_RS11295
ABZR87_RS12585
ABZR87_RS14655
ABZR87_RS14660
ABZR87_RS16545
ABZR87_RS16935
ABZR87_RS17480
ABZR87_RS17485
ABZR87_RS20520
ABZR87_RS20900
ABZR87_RS21810
ABZR87_RS23090
ABZR87_RS23345
3-hydroxyacyl-CoA dehydrogenase:
a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA + NAD+→a 2,3,4-saturated 3-oxoacyl-CoA + NADH + H+
(EC 1.1.1.35)
ABZR87_RS00745
ABZR87_RS07480
ABZR87_RS12585
ABZR87_RS14655
ABZR87_RS23345
Acetyl-CoA C-acyltransferase (in reverse):
a 2,3,4-saturated 3-oxoacyl-CoA + coenzyme A→a 2,3,4-saturated fatty acyl CoA + acetyl-CoA
(EC 2.3.1.16)
ABZR87_RS06305
ABZR87_RS07485
ABZR87_RS07810
ABZR87_RS12575
ABZR87_RS13270
ABZR87_RS13295
ABZR87_RS15790
ABZR87_RS23340
Citrate (Si)-synthase:
acetyl-CoA + oxaloacetate + H2O→citrate + coenzyme A + H+
(EC 2.3.3.1; 2.3.3.16; 2.3.3.3)
ABZR87_RS04350
ABZR87_RS14545
ABZR87_RS17920
Aconitate hydratase:
citrate→cis-aconitate + H2O
(EC 4.2.1.3)
ABZR87_RS14605
ABZR87_RS16735
ABZR87_RS20490
Aconitate hydratase:
cis-aconitate + H2O→D-threo-isocitrate
(EC 4.2.1.3)
ABZR87_RS14605
ABZR87_RS16735
ABZR87_RS20490
Isocitrate lyase:
D-threo-isocitrate→glyoxylate + succinate
(EC 4.1.3.1)
ABZR87_RS08330
ABZR87_RS11590
Malate synthase:
acetyl-CoA + glyoxylate + H2O→(S)-malate + coenzyme A + H+
(EC 2.3.3.9)
ABZR87_RS11625
Succinate dehydrogenase (ubiquinone):
succinate[in] + an electron-transfer quinone→fumarate[in] + an electron-transfer quinol
(EC 1.3.5.1)
ABZR87_RS14560
Fumarate hydratase (in reverse):
fumarate + H2O→(S)-malate
(EC 4.2.1.2)
ABZR87_RS14375
ABZR87_RS18630
Malate dehydrogenase:
(S)-malate + NAD+→oxaloacetate + NADH + H+
(EC 1.1.1.37; 1.1.1.38)
ABZR87_RS14580
Phosphoenolpyruvate carboxykinase (ATP):
oxaloacetate + ATP→phosphoenolpyruvate + ADP + CO2
(EC 4.1.1.49)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information