MetaCyc Pathway: 3-phenylpropanoate degradation in Ralstonia sp. UNC404CL21Col

Add experiment(s):


3-phenylpropanoate + ATP + coenzyme A→3-phenylpropanoyl-CoA + AMP + diphosphate
No genes
3-phenylpropanoyl-CoA + an oxidized electron carrier→(E)-cinnamoyl-CoA + a reduced two electron carrier
No genes
Enoyl-CoA hydratase (in reverse):
(E)-cinnamoyl-CoA + H2O→(S)-3-hydroxy-3-phenylpropanoyl-CoA (EC 4.2.1.17)
ABZR87_RS02095
ABZR87_RS02100
ABZR87_RS06190
ABZR87_RS06470
ABZR87_RS07480
ABZR87_RS07495
ABZR87_RS11295
ABZR87_RS12585
ABZR87_RS14655
ABZR87_RS14660
ABZR87_RS16545
ABZR87_RS16935
ABZR87_RS17480
ABZR87_RS17485
ABZR87_RS20520
ABZR87_RS20900
ABZR87_RS21810
ABZR87_RS23090
ABZR87_RS23345
3-hydroxyacyl-CoA dehydrogenase:
(S)-3-hydroxy-3-phenylpropanoyl-CoA + NAD+→3-oxo-3-phenylpropanoyl-CoA + NADH + H+ (EC 1.1.1.35)
ABZR87_RS00745
ABZR87_RS07480
ABZR87_RS12585
ABZR87_RS14655
ABZR87_RS23345
Acetyl-CoA C-acyltransferase (in reverse):
3-oxo-3-phenylpropanoyl-CoA + coenzyme A→benzoyl-CoA + acetyl-CoA (EC 2.3.1.16)
ABZR87_RS06305
ABZR87_RS07485
ABZR87_RS07810
ABZR87_RS12575
ABZR87_RS13270
ABZR87_RS13295
ABZR87_RS15790
ABZR87_RS23340
Benzoyl-CoA 3-monooxygenase:
benzoyl-CoA + NADPH + dioxygen + H+→3-hydroxybenzoyl-CoA + NADP+ + H2O (EC 1.14.13.58)
No genes
3-hydroxybenzoyl-CoA + a reduced two electron carrier + dioxygen→gentisate + an oxidized electron carrier + coenzyme A + H+
No genes
Gentisate 1,2-dioxygenase:
gentisate + dioxygen→3-maleylpyruvate + H+ (EC 1.13.11.4)
No genes
Maleylpyruvate isomerase:
3-maleylpyruvate→3-fumarylpyruvate (EC 5.2.1.4)
ABZR87_RS06920
3-fumarylpyruvate + H2O→fumarate + pyruvate + H+ (EC 3.7.1.20)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information