MetaCyc Pathway: coenzyme M biosynthesis I in Ralstonia sp. UNC404CL21Col

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Phosphosulfolactate synthase (in reverse):
phosphoenolpyruvate + sulfite + H+→(2R)-phospho-3-sulfolactate (EC 4.4.1.19)
No genes
2-phosphosulfolactate phosphatase:
(2R)-phospho-3-sulfolactate + H2O→(2R)-3-sulfolactate + phosphate (EC 3.1.3.71)
ABZR87_RS11130
(2R)-3-sulfolactate + NAD+→3-sulfopyruvate + NADH + H+ (EC 1.1.1.337)
No genes
Sulfopyruvate decarboxylase:
3-sulfopyruvate + H+→sulfoacetaldehyde + CO2 (EC 4.1.1.79)
No genes
sulfoacetaldehyde + L-cysteine→2-(sulfomethyl)thiazolidine-4-carboxylate + H+ + H2O
No genes
2-(sulfomethyl)thiazolidine-4-carboxylate + a reduced two electron carrier + H+→sulfoethylcysteine + an oxidized electron carrier
No genes
sulfoethylcysteine + H2O→coenzyme M + ammonium + pyruvate
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information