MetaCyc Pathway: gluconeogenesis I in Ralstonia sp. UNC404CL21Col

Malate dehydrogenase (oxaloacetate-decarboxylating): (S)-malate + NAD+→pyruvate + CO2 + NADH (EC 1.1.1.38)

No genes

Malate dehydrogenase: (S)-malate + NAD+→oxaloacetate + NADH + H+ (EC 1.1.1.37; 1.1.1.38)

ABZR87_RS14580

Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)): (S)-malate + NADP+→pyruvate + CO2 + NADPH (EC 1.1.1.40)

ABZR87_RS01565

ABZR87_RS15110

Phosphoenolpyruvate carboxykinase (ATP): oxaloacetate + ATP→phosphoenolpyruvate + ADP + CO2 (EC 4.1.1.49)

No genes

Pyruvate, water dikinase: pyruvate + ATP + H2O→phosphoenolpyruvate + AMP + 2 H+ + phosphate (EC 2.7.9.2)

ABZR87_RS11925

ABZR87_RS16385

Phosphopyruvate hydratase (in reverse): phosphoenolpyruvate + H2O→2-phospho-D-glycerate (EC 4.2.1.11)

ABZR87_RS10470

2-phospho-D-glycerate→3-phospho-D-glycerate (EC 5.4.2.12)

ABZR87_RS06750

Phosphoglycerate kinase: 3-phospho-D-glycerate + ATP→3-phospho-D-glyceroyl phosphate + ADP (EC 2.7.2.3)

ABZR87_RS08065

Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) (in reverse): 3-phospho-D-glyceroyl phosphate + NADH + H+→D-glyceraldehyde 3-phosphate + NAD+ + phosphate (EC 1.2.1.12)

ABZR87_RS01435

Fructose-bisphosphate aldolase (in reverse): D-glyceraldehyde 3-phosphate + glycerone phosphate→β-D-fructofuranose 1,6-bisphosphate (EC 4.1.2.13)

ABZR87_RS08075

Fructose-bisphosphatase: β-D-fructofuranose 1,6-bisphosphate + H2O→β-D-fructofuranose 6-phosphate + phosphate (EC 3.1.3.11)

ABZR87_RS15125

Triose-phosphate isomerase (in reverse): glycerone phosphate→D-glyceraldehyde 3-phosphate (EC 5.3.1.1)

ABZR87_RS14895

Glucose-6-phosphate isomerase (in reverse): β-D-fructofuranose 6-phosphate→α-D-glucose 6-phosphate (EC 5.3.1.9)

ABZR87_RS12745

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information