MetaCyc Pathway: superpathway of L-threonine biosynthesis in Paraburkholderia bryophila 376MFSha3.1

Add experiment(s):


Aspartate transaminase (in reverse):
oxaloacetate + L-glutamate→L-aspartate + 2-oxoglutarate (EC 2.6.1.1)
H281DRAFT_00273
H281DRAFT_00432
H281DRAFT_00809
H281DRAFT_00920
H281DRAFT_01048
H281DRAFT_01557
H281DRAFT_01577
H281DRAFT_02293
H281DRAFT_02907
H281DRAFT_03132
H281DRAFT_03686
H281DRAFT_03705
H281DRAFT_04024
H281DRAFT_04101
H281DRAFT_04597
H281DRAFT_05051
H281DRAFT_05099
H281DRAFT_05339
H281DRAFT_05564
H281DRAFT_05880
H281DRAFT_06094
H281DRAFT_06439
Aspartate kinase:
L-aspartate + ATP→L-aspartyl-4-phosphate + ADP (EC 2.7.2.4)
H281DRAFT_00550
Aspartate-semialdehyde dehydrogenase (in reverse):
L-aspartyl-4-phosphate + NADPH + H+→L-aspartate 4-semialdehyde + NADP+ + phosphate (EC 1.2.1.11)
H281DRAFT_06071
Homoserine dehydrogenase (in reverse):
L-aspartate 4-semialdehyde + NAD(P)H + H+→L-homoserine + NAD(P)+ (EC 1.1.1.3)
H281DRAFT_00810
Homoserine kinase:
L-homoserine + ATP→O-phospho-L-homoserine + ADP + H+ (EC 2.7.1.39)
H281DRAFT_06029
Threonine synthase:
O-phospho-L-homoserine + H2O→L-threonine + phosphate (EC 4.2.3.1)
H281DRAFT_00811

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information