MetaCyc Pathway: anaerobic energy metabolism (invertebrates, mitochondrial) in Paraburkholderia bryophila 376MFSha3.1

Malate dehydrogenase (oxaloacetate-decarboxylating): (S)-malate + NAD+→CO2 + pyruvate + NADH (EC 1.1.1.38)

H281DRAFT_00026

Fumarate hydratase: (S)-malate→fumarate + H2O (EC 4.2.1.2)

H281DRAFT_00025

H281DRAFT_02592

H281DRAFT_04314

H281DRAFT_04956

pyruvate + coenzyme A + NAD+→CO2 + acetyl-CoA + NADH (EC 1.2.1.104)

H281DRAFT_00466

H281DRAFT_00467

Succinate dehydrogenase (ubiquinone) (in reverse): fumarate[in] + a rhodoquinol→succinate[in] + a rhodoquinone (EC 1.3.5.1)

No genes

acetyl-CoA + succinate→acetate + succinyl-CoA (EC 2.8.3.18)

H281DRAFT_05262

succinate + propanoyl-CoA→succinyl-CoA + propanoate (EC 2.8.3.27)

No genes

Methylmalonyl-CoA mutase (in reverse): succinyl-CoA→(R)-methylmalonyl-CoA (EC 5.4.99.2)

H281DRAFT_01038

H281DRAFT_02110

Succinate--CoA ligase (ADP-forming) (in reverse): succinyl-CoA + ADP + phosphate→succinate + ATP + coenzyme A (EC 6.2.1.5)

H281DRAFT_04204

H281DRAFT_04205

Methylmalonyl-CoA epimerase: (R)-methylmalonyl-CoA→(S)-methylmalonyl-CoA (EC 5.1.99.1)

No genes

Propionyl-CoA carboxylase (in reverse): (S)-methylmalonyl-CoA + ADP + H+ + phosphate→propanoyl-CoA + ATP + hydrogen carbonate (EC 6.4.1.3)

H281DRAFT_00548

H281DRAFT_06064

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information