MetaCyc Pathway: pyruvate fermentation to butanol II (engineered) in Paraburkholderia bryophila 376MFSha3.1

Add experiment(s):


Acetyl-CoA C-acyltransferase:
2 acetyl-CoA→acetoacetyl-CoA + coenzyme A
(EC 2.3.1.16; 2.3.1.9)
H281DRAFT_00852
H281DRAFT_00857
H281DRAFT_00917
H281DRAFT_01504
H281DRAFT_02089
H281DRAFT_04626
H281DRAFT_05130
H281DRAFT_05518
H281DRAFT_05559
H281DRAFT_05723
H281DRAFT_06132
3-hydroxyacyl-CoA dehydrogenase (in reverse):
acetoacetyl-CoA + NADH + H+→(S)-3-hydroxybutanoyl-CoA + NAD+
(EC 1.1.1.35)
H281DRAFT_00361
H281DRAFT_00916
H281DRAFT_03517
H281DRAFT_04595
H281DRAFT_04625
H281DRAFT_05521
H281DRAFT_06131
(S)-3-hydroxybutanoyl-CoA→crotonyl-CoA + H2O (EC 4.2.1.150)
H281DRAFT_00361
H281DRAFT_00653
H281DRAFT_00756
H281DRAFT_00916
H281DRAFT_01137
H281DRAFT_01179
H281DRAFT_01187
H281DRAFT_01670
H281DRAFT_01774
H281DRAFT_02068
H281DRAFT_02497
H281DRAFT_02514
H281DRAFT_02515
H281DRAFT_02677
H281DRAFT_02741
H281DRAFT_02927
H281DRAFT_03491
H281DRAFT_03701
H281DRAFT_03739
H281DRAFT_03908
H281DRAFT_04625
H281DRAFT_04627
H281DRAFT_04744
H281DRAFT_05516
H281DRAFT_05977
Trans-2-enoyl-CoA reductase (NAD(+)) (in reverse):
crotonyl-CoA + NADH + H+→butanoyl-CoA + NAD+
(EC 1.3.1.44)
H281DRAFT_00726
H281DRAFT_01180
H281DRAFT_01204
H281DRAFT_02091
H281DRAFT_03362
H281DRAFT_05133
Butanal dehydrogenase (in reverse):
butanoyl-CoA + NAD(P)H + H+→1-butanal + coenzyme A + NAD(P)+
(EC 1.2.1.57)
No genes
1-butanal + NADH + H+→butan-1-ol + NAD+
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information