MetaCyc Pathway: benzoate biosynthesis I (CoA-dependent, β-oxidative) in Paraburkholderia bryophila 376MFSha3.1

MetaCyc Pathway: benzoate biosynthesis I (CoA-dependent, β-oxidative) in Paraburkholderia bryophila 376MFSha3.1

Phenylalanine ammonia-lyase:
L-phenylalanine→trans-cinnamate + ammonium (EC 4.3.1.24; 4.3.1.25; 5.4.3.10)

No genes

trans-cinnamate + ATP + coenzyme A→(E)-cinnamoyl-CoA + AMP + diphosphate

No genes

Enoyl-CoA hydratase (in reverse):
(E)-cinnamoyl-CoA + H₂O→(S)-3-hydroxy-3-phenylpropanoyl-CoA (EC 4.2.1.17)

H281DRAFT_00361

H281DRAFT_00373

H281DRAFT_00653

H281DRAFT_00756

H281DRAFT_00916

H281DRAFT_01137

H281DRAFT_01179

H281DRAFT_01187

H281DRAFT_01199

H281DRAFT_01200

H281DRAFT_01276

H281DRAFT_01670

H281DRAFT_01774

H281DRAFT_02068

H281DRAFT_02497

H281DRAFT_02514

H281DRAFT_02515

H281DRAFT_02677

H281DRAFT_02741

H281DRAFT_02927

H281DRAFT_03491

H281DRAFT_03701

H281DRAFT_03739

H281DRAFT_03908

H281DRAFT_04594

H281DRAFT_04595

H281DRAFT_04625

H281DRAFT_04627

H281DRAFT_04744

H281DRAFT_05516

H281DRAFT_05722

H281DRAFT_05725

H281DRAFT_05977

3-hydroxyacyl-CoA dehydrogenase:
(S)-3-hydroxy-3-phenylpropanoyl-CoA + NAD⁺→3-oxo-3-phenylpropanoyl-CoA + NADH + H⁺ (EC 1.1.1.35)

H281DRAFT_00361

H281DRAFT_00916

H281DRAFT_03517

H281DRAFT_04595

H281DRAFT_04625

H281DRAFT_06131

Acetyl-CoA C-acyltransferase (in reverse):
3-oxo-3-phenylpropanoyl-CoA + coenzyme A→benzoyl-CoA + acetyl-CoA (EC 2.3.1.16)

H281DRAFT_00852

H281DRAFT_00857

H281DRAFT_00917

H281DRAFT_01504

H281DRAFT_02089

H281DRAFT_04626

H281DRAFT_05130

H281DRAFT_05559

H281DRAFT_05723

H281DRAFT_06132

benzoyl-CoA + H₂O→benzoate + coenzyme A + H⁺

No genes

benzoyl-CoA + benzyl alcohol→benzyl benzoate + coenzyme A (EC 2.3.1.196)

No genes

benzyl benzoate + H₂O→benzoate + benzyl alcohol + H⁺

No genes

Benzoate--CoA ligase:
benzoate + ATP + coenzyme A→benzoyl-CoA + AMP + diphosphate (EC 6.2.1.25)

H281DRAFT_00369

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information