MetaCyc Pathway: acetyl-CoA fermentation to butanoate in Paraburkholderia bryophila 376MFSha3.1

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Acetyl-CoA C-acyltransferase:
2 acetyl-CoA→acetoacetyl-CoA + coenzyme A
(EC 2.3.1.16; 2.3.1.9)
H281DRAFT_00852
H281DRAFT_00857
H281DRAFT_00917
H281DRAFT_01504
H281DRAFT_02089
H281DRAFT_04626
H281DRAFT_05130
H281DRAFT_05518
H281DRAFT_05559
H281DRAFT_05723
H281DRAFT_06132
Phosphate acetyltransferase:
acetyl-CoA + phosphate→acetyl phosphate + coenzyme A
(EC 2.3.1.8)
H281DRAFT_01410
Acetate kinase (in reverse):
acetyl phosphate + ADP→acetate + ATP
(EC 2.7.2.1; 2.7.2.15)
H281DRAFT_00303
H281DRAFT_01409
H281DRAFT_02796
Acetoacetyl-CoA reductase (in reverse):
acetoacetyl-CoA + NADPH + H+→(3R)-3-hydroxybutanoyl-CoA + NADP+
(EC 1.1.1.36)
H281DRAFT_00853
H281DRAFT_02508
3-hydroxybutyryl-CoA dehydratase:
(3R)-3-hydroxybutanoyl-CoA→crotonyl-CoA + H2O
(EC 4.2.1.55)
H281DRAFT_03172
crotonyl-CoA[cytosol] + 2 NADH[cytosol] + 2 an oxidized ferredoxin [iron-sulfur] cluster[cytosol]→butanoyl-CoA[cytosol] + 2 NAD+[cytosol] + 2 a reduced ferredoxin [iron-sulfur] cluster[cytosol] (EC 1.3.1.109)
No genes
Propionate CoA-transferase:
acetate + butanoyl-CoA→acetyl-CoA + butanoate
(EC 2.8.3.1; 2.8.3.8)
H281DRAFT_02525

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information