MetaCyc Pathway: L-glutamate and L-glutamine biosynthesis in Paraburkholderia bryophila 376MFSha3.1

Add experiment(s):


Glutamate dehydrogenase (NAD(P)(+)) (in reverse):
2-oxoglutarate + ammonium + NAD(P)H + H+→L-glutamate + NAD(P)+ + H2O
(EC 1.4.1.3)
H281DRAFT_04271
Glutamate synthase (ferredoxin) (in reverse):
2-oxoglutarate + L-glutamine + 2 H+ + 2 a reduced ferredoxin [iron-sulfur] cluster→2 L-glutamate + 2 an oxidized ferredoxin [iron-sulfur] cluster
(EC 1.4.7.1)
H281DRAFT_04650
Glutamate synthase (NADH) (in reverse):
2-oxoglutarate + L-glutamine + NADH + H+→2 L-glutamate + NAD+
(EC 1.4.1.14)
H281DRAFT_00378
H281DRAFT_05621
Glutamate synthase (NADPH):
L-glutamine + H2O→L-glutamate + ammonia + H+
(EC 1.4.1.13; 1.4.1.14; 1.4.7.1; 2.6.1.85; 3.5.1.2; 3.5.1.38; 4.1.3.27; 4.3.2.10; 4.3.3.6; 6.3.4.2; 6.3.5.13; 6.3.5.2; 6.3.5.4; 6.3.5.5; 6.3.5.6; 6.3.5.7)
H281DRAFT_00378
H281DRAFT_00495
H281DRAFT_00637
H281DRAFT_01685
H281DRAFT_02165
H281DRAFT_02220
H281DRAFT_02221
H281DRAFT_02222
H281DRAFT_02364
H281DRAFT_03243
H281DRAFT_03954
H281DRAFT_03959
H281DRAFT_04402
H281DRAFT_04403
H281DRAFT_04650
H281DRAFT_04702
H281DRAFT_05620
H281DRAFT_05621
H281DRAFT_05714
H281DRAFT_05715
H281DRAFT_05933
H281DRAFT_05994
H281DRAFT_06113
Glutamate--ammonia ligase:
L-glutamate + ammonium + ATP→L-glutamine + ADP + H+ + phosphate
(EC 6.3.1.2)
H281DRAFT_00452
H281DRAFT_01081
H281DRAFT_03844
Glutamate dehydrogenase (NADP(+)) (in reverse):
2-oxoglutarate + ammonium + NADPH + H+→L-glutamate + NADP+ + H2O
(EC 1.4.1.4)
H281DRAFT_04271
Glutamate synthase (NADPH) (in reverse):
2-oxoglutarate + ammonia + NADPH + 2 H+→L-glutamate + NADP+ + H2O
(EC 1.4.1.13; 1.4.1.14)
H281DRAFT_00378
H281DRAFT_03243
H281DRAFT_05620
H281DRAFT_05621
H281DRAFT_05994

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information