MetaCyc Pathway: superpathway of fatty acid biosynthesis II (plant) in Paraburkholderia bryophila 376MFSha3.1

Add experiment(s):


acetyl-CoA + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine→malonyl-CoA + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine (EC 2.1.3.15)
H281DRAFT_00548
H281DRAFT_06064
[Acyl-carrier-protein] S-malonyltransferase:
malonyl-CoA + a soluble [acyl-carrier protein]→a malonyl-[acp] + coenzyme A (EC 2.3.1.39)
H281DRAFT_04350
H281DRAFT_05276
Beta-ketoacyl-acyl-carrier-protein synthase III:
acetyl-CoA + a malonyl-[acp] + H+→an acetoacetyl-[acp] + CO2 + coenzyme A (EC 2.3.1.180)
H281DRAFT_04349
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
an acetoacetyl-[acp] + NADPH + H+→a (3R)-3-hydroxybutanoyl-[acp] + NADP+ (EC 1.1.1.100)
H281DRAFT_00212
H281DRAFT_00643
H281DRAFT_00677
H281DRAFT_00796
H281DRAFT_01019
H281DRAFT_01131
H281DRAFT_01188
H281DRAFT_01230
H281DRAFT_01561
H281DRAFT_01659
H281DRAFT_01729
H281DRAFT_01811
H281DRAFT_02429
H281DRAFT_02507
H281DRAFT_02561
H281DRAFT_02581
H281DRAFT_03080
H281DRAFT_03241
H281DRAFT_03637
H281DRAFT_03641
H281DRAFT_03712
H281DRAFT_03713
H281DRAFT_03748
H281DRAFT_03856
H281DRAFT_03972
H281DRAFT_04114
H281DRAFT_04145
H281DRAFT_04351
H281DRAFT_04524
H281DRAFT_04910
H281DRAFT_05132
H281DRAFT_05459
H281DRAFT_05476
H281DRAFT_05497
H281DRAFT_05552
H281DRAFT_05556
H281DRAFT_05863
H281DRAFT_06109
H281DRAFT_06110
H281DRAFT_06296
H281DRAFT_06377
H281DRAFT_06505
H281DRAFT_06506
H281DRAFT_06507
H281DRAFT_06578
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxybutanoyl-[acp]→a (2E)-but-2-enoyl-[acp] + H2O (EC 4.2.1.59)
H281DRAFT_00621
H281DRAFT_02426
H281DRAFT_06622
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a (2E)-but-2-enoyl-[acp] + NADH + H+→a butanoyl-[acp] + NAD+ (EC 1.3.1.9)
H281DRAFT_00003
H281DRAFT_02163
Beta-ketoacyl-acyl-carrier-protein synthase II:
a butanoyl-[acp] + a malonyl-[acp] + H+→a 3-oxohexanoyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
H281DRAFT_03970
H281DRAFT_03971
H281DRAFT_03974
H281DRAFT_04353
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a 3-oxohexanoyl-[acp] + NADPH + H+→a (3R)-3-hydroxyhexanoyl-[acp] + NADP+ (EC 1.1.1.100)
H281DRAFT_00212
H281DRAFT_00643
H281DRAFT_00677
H281DRAFT_00796
H281DRAFT_01019
H281DRAFT_01131
H281DRAFT_01188
H281DRAFT_01230
H281DRAFT_01561
H281DRAFT_01659
H281DRAFT_01729
H281DRAFT_01811
H281DRAFT_02429
H281DRAFT_02507
H281DRAFT_02561
H281DRAFT_02581
H281DRAFT_03080
H281DRAFT_03241
H281DRAFT_03637
H281DRAFT_03641
H281DRAFT_03712
H281DRAFT_03713
H281DRAFT_03748
H281DRAFT_03856
H281DRAFT_03972
H281DRAFT_04114
H281DRAFT_04145
H281DRAFT_04351
H281DRAFT_04524
H281DRAFT_04910
H281DRAFT_05132
H281DRAFT_05459
H281DRAFT_05476
H281DRAFT_05497
H281DRAFT_05552
H281DRAFT_05556
H281DRAFT_05863
H281DRAFT_06109
H281DRAFT_06110
H281DRAFT_06296
H281DRAFT_06377
H281DRAFT_06505
H281DRAFT_06506
H281DRAFT_06507
H281DRAFT_06578
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxyhexanoyl-[acp]→a (2E)-hex-2-enoyl-[acp] + H2O (EC 4.2.1.59)
H281DRAFT_00621
H281DRAFT_02426
H281DRAFT_06622
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a (2E)-hex-2-enoyl-[acp] + NADH + H+→a hexanoyl-[acp] + NAD+ (EC 1.3.1.9)
H281DRAFT_00003
H281DRAFT_02163
Beta-ketoacyl-acyl-carrier-protein synthase II:
a hexanoyl-[acp] + a malonyl-[acp] + H+→a 3-oxooctanoyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
H281DRAFT_03970
H281DRAFT_03971
H281DRAFT_03974
H281DRAFT_04353
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a 3-oxooctanoyl-[acp] + NADPH + H+→a (3R)-3-hydroxyoctanoyl-[acp] + NADP+ (EC 1.1.1.100)
H281DRAFT_00212
H281DRAFT_00643
H281DRAFT_00677
H281DRAFT_00796
H281DRAFT_01019
H281DRAFT_01131
H281DRAFT_01188
H281DRAFT_01230
H281DRAFT_01561
H281DRAFT_01659
H281DRAFT_01729
H281DRAFT_01811
H281DRAFT_02429
H281DRAFT_02507
H281DRAFT_02561
H281DRAFT_02581
H281DRAFT_03080
H281DRAFT_03241
H281DRAFT_03637
H281DRAFT_03641
H281DRAFT_03712
H281DRAFT_03713
H281DRAFT_03748
H281DRAFT_03856
H281DRAFT_03972
H281DRAFT_04114
H281DRAFT_04145
H281DRAFT_04351
H281DRAFT_04524
H281DRAFT_04910
H281DRAFT_05132
H281DRAFT_05459
H281DRAFT_05476
H281DRAFT_05497
H281DRAFT_05552
H281DRAFT_05556
H281DRAFT_05863
H281DRAFT_06109
H281DRAFT_06110
H281DRAFT_06296
H281DRAFT_06377
H281DRAFT_06505
H281DRAFT_06506
H281DRAFT_06507
H281DRAFT_06578
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxyoctanoyl-[acp]→a (2E)-oct-2-enoyl-[acp] + H2O (EC 4.2.1.59)
H281DRAFT_00621
H281DRAFT_02426
H281DRAFT_06622
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a (2E)-oct-2-enoyl-[acp] + NADH + H+→an octanoyl-[acp] + NAD+ (EC 1.3.1.9)
H281DRAFT_00003
H281DRAFT_02163
Beta-ketoacyl-acyl-carrier-protein synthase II:
an octanoyl-[acp] + a malonyl-[acp] + H+→a 3-oxodecanoyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
H281DRAFT_03970
H281DRAFT_03971
H281DRAFT_03974
H281DRAFT_04353
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a 3-oxodecanoyl-[acp] + NADPH + H+→a (3R)-3-hydroxydecanoyl-[acp] + NADP+ (EC 1.1.1.100)
H281DRAFT_00212
H281DRAFT_00643
H281DRAFT_00677
H281DRAFT_00796
H281DRAFT_01019
H281DRAFT_01131
H281DRAFT_01188
H281DRAFT_01230
H281DRAFT_01561
H281DRAFT_01659
H281DRAFT_01729
H281DRAFT_01811
H281DRAFT_02429
H281DRAFT_02507
H281DRAFT_02561
H281DRAFT_02581
H281DRAFT_03080
H281DRAFT_03241
H281DRAFT_03637
H281DRAFT_03641
H281DRAFT_03712
H281DRAFT_03713
H281DRAFT_03748
H281DRAFT_03856
H281DRAFT_03972
H281DRAFT_04114
H281DRAFT_04145
H281DRAFT_04351
H281DRAFT_04524
H281DRAFT_04910
H281DRAFT_05132
H281DRAFT_05459
H281DRAFT_05476
H281DRAFT_05497
H281DRAFT_05552
H281DRAFT_05556
H281DRAFT_05863
H281DRAFT_06109
H281DRAFT_06110
H281DRAFT_06296
H281DRAFT_06377
H281DRAFT_06505
H281DRAFT_06506
H281DRAFT_06507
H281DRAFT_06578
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxydecanoyl-[acp]→a (2E)-dec-2-enoyl-[acp] + H2O (EC 4.2.1.59)
H281DRAFT_00621
H281DRAFT_02426
H281DRAFT_06622
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a (2E)-dec-2-enoyl-[acp] + NADH + H+→a decanoyl-[acp] + NAD+ (EC 1.3.1.9)
H281DRAFT_00003
H281DRAFT_02163
Beta-ketoacyl-acyl-carrier-protein synthase II:
a decanoyl-[acp] + a malonyl-[acp] + H+→a 3-oxododecanoyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
H281DRAFT_03970
H281DRAFT_03971
H281DRAFT_03974
H281DRAFT_04353
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a 3-oxododecanoyl-[acp] + NADPH + H+→a (3R)-3-hydroxydodecanoyl-[acp] + NADP+ (EC 1.1.1.100)
H281DRAFT_00212
H281DRAFT_00643
H281DRAFT_00677
H281DRAFT_00796
H281DRAFT_01019
H281DRAFT_01131
H281DRAFT_01188
H281DRAFT_01230
H281DRAFT_01561
H281DRAFT_01659
H281DRAFT_01729
H281DRAFT_01811
H281DRAFT_02429
H281DRAFT_02507
H281DRAFT_02561
H281DRAFT_02581
H281DRAFT_03080
H281DRAFT_03241
H281DRAFT_03637
H281DRAFT_03641
H281DRAFT_03712
H281DRAFT_03713
H281DRAFT_03748
H281DRAFT_03856
H281DRAFT_03972
H281DRAFT_04114
H281DRAFT_04145
H281DRAFT_04351
H281DRAFT_04524
H281DRAFT_04910
H281DRAFT_05132
H281DRAFT_05459
H281DRAFT_05476
H281DRAFT_05497
H281DRAFT_05552
H281DRAFT_05556
H281DRAFT_05863
H281DRAFT_06109
H281DRAFT_06110
H281DRAFT_06296
H281DRAFT_06377
H281DRAFT_06505
H281DRAFT_06506
H281DRAFT_06507
H281DRAFT_06578
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxydodecanoyl-[acp]→a (2E)-dodec-2-enoyl-[acp] + H2O (EC 4.2.1.59)
H281DRAFT_00621
H281DRAFT_02426
H281DRAFT_06622
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a (2E)-dodec-2-enoyl-[acp] + NADH + H+→a dodecanoyl-[acp] + NAD+ (EC 1.3.1.9)
H281DRAFT_00003
H281DRAFT_02163
Dodecanoyl-[acyl-carrier-protein] hydrolase:
a dodecanoyl-[acp][nil] + H2O[nil]→laurate[nil] + a soluble [acyl-carrier protein][nil] + H+[nil] (EC 3.1.2.21)
No genes
Beta-ketoacyl-acyl-carrier-protein synthase II:
a dodecanoyl-[acp] + a malonyl-[acp] + H+→a 3-oxotetradecanoyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
H281DRAFT_03970
H281DRAFT_03971
H281DRAFT_03974
H281DRAFT_04353
Butyrate--CoA ligase:
laurate + ATP + coenzyme A→lauroyl-CoA + AMP + diphosphate (EC 6.2.1.2; 6.2.1.3)
H281DRAFT_02398
H281DRAFT_05129
H281DRAFT_06226
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a 3-oxotetradecanoyl-[acp] + NADPH + H+→a (3R)-3-hydroxytetradecanoyl-[acp] + NADP+ (EC 1.1.1.100)
H281DRAFT_00212
H281DRAFT_00643
H281DRAFT_00677
H281DRAFT_00796
H281DRAFT_01019
H281DRAFT_01131
H281DRAFT_01188
H281DRAFT_01230
H281DRAFT_01561
H281DRAFT_01659
H281DRAFT_01729
H281DRAFT_01811
H281DRAFT_02429
H281DRAFT_02507
H281DRAFT_02561
H281DRAFT_02581
H281DRAFT_03080
H281DRAFT_03241
H281DRAFT_03637
H281DRAFT_03641
H281DRAFT_03712
H281DRAFT_03713
H281DRAFT_03748
H281DRAFT_03856
H281DRAFT_03972
H281DRAFT_04114
H281DRAFT_04145
H281DRAFT_04351
H281DRAFT_04524
H281DRAFT_04910
H281DRAFT_05132
H281DRAFT_05459
H281DRAFT_05476
H281DRAFT_05497
H281DRAFT_05552
H281DRAFT_05556
H281DRAFT_05863
H281DRAFT_06109
H281DRAFT_06110
H281DRAFT_06296
H281DRAFT_06377
H281DRAFT_06505
H281DRAFT_06506
H281DRAFT_06507
H281DRAFT_06578
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxytetradecanoyl-[acp]→a (2E)-tetradec-2-enoyl-[acp] + H2O (EC 4.2.1.59)
H281DRAFT_00621
H281DRAFT_02426
H281DRAFT_06622
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a (2E)-tetradec-2-enoyl-[acp] + NADH + H+→a myristoyl-[acp] + NAD+ (EC 1.3.1.9)
H281DRAFT_00003
H281DRAFT_02163
Beta-ketoacyl-acyl-carrier-protein synthase II:
a myristoyl-[acp] + a malonyl-[acp] + H+→a 3-oxohexadecanoyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
H281DRAFT_03970
H281DRAFT_03971
H281DRAFT_03974
H281DRAFT_04353
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a 3-oxohexadecanoyl-[acp] + NADPH + H+→a (3R)-3-hydroxyhexadecanoyl-[acp] + NADP+ (EC 1.1.1.100)
H281DRAFT_00212
H281DRAFT_00643
H281DRAFT_00677
H281DRAFT_00796
H281DRAFT_01019
H281DRAFT_01131
H281DRAFT_01188
H281DRAFT_01230
H281DRAFT_01561
H281DRAFT_01659
H281DRAFT_01729
H281DRAFT_01811
H281DRAFT_02429
H281DRAFT_02507
H281DRAFT_02561
H281DRAFT_02581
H281DRAFT_03080
H281DRAFT_03241
H281DRAFT_03637
H281DRAFT_03641
H281DRAFT_03712
H281DRAFT_03713
H281DRAFT_03748
H281DRAFT_03856
H281DRAFT_03972
H281DRAFT_04114
H281DRAFT_04145
H281DRAFT_04351
H281DRAFT_04524
H281DRAFT_04910
H281DRAFT_05132
H281DRAFT_05459
H281DRAFT_05476
H281DRAFT_05497
H281DRAFT_05552
H281DRAFT_05556
H281DRAFT_05863
H281DRAFT_06109
H281DRAFT_06110
H281DRAFT_06296
H281DRAFT_06377
H281DRAFT_06505
H281DRAFT_06506
H281DRAFT_06507
H281DRAFT_06578
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxyhexadecanoyl-[acp]→a (2E)-hexadec-2-enoyl-[acp] + H2O (EC 4.2.1.59)
H281DRAFT_00621
H281DRAFT_02426
H281DRAFT_06622
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a (2E)-hexadec-2-enoyl-[acp] + NADH + H+→a palmitoyl-[acp] + NAD+ (EC 1.3.1.9)
H281DRAFT_00003
H281DRAFT_02163
Oleoyl-[acyl-carrier-protein] hydrolase:
a palmitoyl-[acp] + H2O→palmitate + a soluble [acyl-carrier protein] + H+ (EC 3.1.2.14)
No genes
Beta-ketoacyl-acyl-carrier-protein synthase I:
a palmitoyl-[acp] + a malonyl-[acp] + H+→a 3-oxooctadecanoyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.41)
H281DRAFT_03970
H281DRAFT_03971
H281DRAFT_03974
Long-chain-fatty-acid--CoA ligase:
palmitate + ATP + coenzyme A→palmitoyl-CoA + AMP + diphosphate (EC 6.2.1.3)
H281DRAFT_02398
H281DRAFT_05129
H281DRAFT_06226
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a 3-oxooctadecanoyl-[acp] + NADPH + H+→a (3R)-3-hydroxyoctadecanoyl-[acp] + NADP+ (EC 1.1.1.100)
H281DRAFT_00212
H281DRAFT_00643
H281DRAFT_00677
H281DRAFT_00796
H281DRAFT_01019
H281DRAFT_01131
H281DRAFT_01188
H281DRAFT_01230
H281DRAFT_01561
H281DRAFT_01659
H281DRAFT_01729
H281DRAFT_01811
H281DRAFT_02429
H281DRAFT_02507
H281DRAFT_02561
H281DRAFT_02581
H281DRAFT_03080
H281DRAFT_03241
H281DRAFT_03637
H281DRAFT_03641
H281DRAFT_03712
H281DRAFT_03713
H281DRAFT_03748
H281DRAFT_03856
H281DRAFT_03972
H281DRAFT_04114
H281DRAFT_04145
H281DRAFT_04351
H281DRAFT_04524
H281DRAFT_04910
H281DRAFT_05132
H281DRAFT_05459
H281DRAFT_05476
H281DRAFT_05497
H281DRAFT_05552
H281DRAFT_05556
H281DRAFT_05863
H281DRAFT_06109
H281DRAFT_06110
H281DRAFT_06296
H281DRAFT_06377
H281DRAFT_06505
H281DRAFT_06506
H281DRAFT_06507
H281DRAFT_06578
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxyoctadecanoyl-[acp]→a (2E)-octadec-2-enoyl-[acp] + H2O (EC 4.2.1.59)
H281DRAFT_00621
H281DRAFT_02426
H281DRAFT_06622
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a (2E)-octadec-2-enoyl-[acp] + NADH + H+→a stearoyl-[acp] + NAD+ (EC 1.3.1.9)
H281DRAFT_00003
H281DRAFT_02163
Acyl-[acyl-carrier-protein] desaturase:
a stearoyl-[acp] + dioxygen + 2 H+ + 2 a reduced ferredoxin [iron-sulfur] cluster→an oleoyl-[acp] + 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O (EC 1.14.19.2)
No genes
Oleoyl-[acyl-carrier-protein] hydrolase:
a stearoyl-[acp] + H2O→stearate + a soluble [acyl-carrier protein] + H+ (EC 3.1.2.14)
No genes
Oleoyl-[acyl-carrier-protein] hydrolase:
an oleoyl-[acp] + H2O→oleate + a soluble [acyl-carrier protein] + H+ (EC 3.1.2.14)
No genes
Long-chain-fatty-acid--CoA ligase:
stearate + ATP + coenzyme A→stearoyl-CoA + AMP + diphosphate (EC 6.2.1.3)
H281DRAFT_02398
H281DRAFT_05129
H281DRAFT_06226
Long-chain-fatty-acid--CoA ligase:
oleate + ATP + coenzyme A→oleoyl-CoA + AMP + diphosphate (EC 6.2.1.3)
H281DRAFT_02398
H281DRAFT_05129
H281DRAFT_06226

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information