MetaCyc Pathway: mixed acid fermentation in Paraburkholderia bryophila 376MFSha3.1

Add experiment(s):


Phosphoenolpyruvate carboxylase (in reverse):
phosphoenolpyruvate + hydrogen carbonate→oxaloacetate + phosphate (EC 4.1.1.31)
H281DRAFT_00197
Pyruvate kinase (in reverse):
phosphoenolpyruvate + ADP + H+→pyruvate + ATP (EC 2.7.1.40)
H281DRAFT_04189
D-lactate dehydrogenase (in reverse):
pyruvate + NADH + H+→(R)-lactate + NAD+ (EC 1.1.1.28)
H281DRAFT_01850
H281DRAFT_04746
Malate dehydrogenase (in reverse):
oxaloacetate + NADH + H+→(S)-malate + NAD+ (EC 1.1.1.37; 1.1.1.38)
H281DRAFT_00026
H281DRAFT_02928
H281DRAFT_05436
H281DRAFT_06632
Formate C-acetyltransferase (in reverse):
pyruvate + coenzyme A→acetyl-CoA + formate (EC 2.3.1.54)
No genes
Acetaldehyde dehydrogenase (acetylating) (in reverse):
acetyl-CoA + NADH + H+→acetaldehyde + coenzyme A + NAD+ (EC 1.2.1.10)
H281DRAFT_01665
Citrate (Si)-synthase:
acetyl-CoA + oxaloacetate + H2O→citrate + coenzyme A + H+ (EC 2.3.3.1; 2.3.3.16; 2.3.3.3)
H281DRAFT_04099
H281DRAFT_05547
H281DRAFT_06117
formate + H+→CO2 + H2
No genes
Fumarate hydratase:
(S)-malate→fumarate + H2O (EC 4.2.1.2)
H281DRAFT_00025
H281DRAFT_02592
H281DRAFT_04314
H281DRAFT_04956
Phosphate acetyltransferase:
acetyl-CoA + phosphate→acetyl phosphate + coenzyme A (EC 2.3.1.8)
H281DRAFT_01410
Acetate kinase (in reverse):
acetyl phosphate + ADP→acetate + ATP (EC 2.7.2.1; 2.7.2.15)
H281DRAFT_00303
H281DRAFT_01409
H281DRAFT_02796
Aconitate hydratase:
citrate→cis-aconitate + H2O (EC 4.2.1.3)
H281DRAFT_02981
H281DRAFT_06210
H281DRAFT_06606
Alcohol dehydrogenase (in reverse):
acetaldehyde + NADH + H+→ethanol + NAD+ (EC 1.1.1.1)
H281DRAFT_01050
H281DRAFT_01171
H281DRAFT_01251
H281DRAFT_02579
H281DRAFT_02988
H281DRAFT_03803
H281DRAFT_04166
H281DRAFT_05379
H281DRAFT_05508
Succinate dehydrogenase (ubiquinone):
fumarate[in] + a menaquinol→succinate[in] + a menaquinone (EC 1.3.5.1)
No genes
Aconitate hydratase:
cis-aconitate + H2O→D-threo-isocitrate (EC 4.2.1.3)
H281DRAFT_02981
H281DRAFT_06210
H281DRAFT_06606
Isocitrate dehydrogenase (NADP(+)):
D-threo-isocitrate + NADP+→CO2 + 2-oxoglutarate + NADPH (EC 1.1.1.42)
H281DRAFT_03806
H281DRAFT_04085

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information