MetaCyc Pathway: ceramide degradation by α-oxidation in Burkholderia phytofirmans PsJN

Add experiment(s):


a phytoceramide + 2 a ferrocytochrome b5 + dioxygen + 2 H+→a (2'R)-2'-hydroxy-phytoceramide + 2 a ferricytochrome b5 + H2O (EC 1.14.18.6)
No genes
Ceramidase:
a (2'R)-2'-hydroxy-phytoceramide + H2O→a (2R)-2-hydroxy even numbered straight chain 2,3,4-saturated fatty acid + a phytosphingosine
(EC 3.5.1.23)
No genes
a (2R)-2-hydroxy even numbered straight chain 2,3,4-saturated fatty acid + ATP + coenzyme A→a (R)-2-hydroxy even numbered straight chain 2,3,4-saturated fatty acyl CoA + AMP + diphosphate
No genes
a (R)-2-hydroxy even numbered straight chain 2,3,4-saturated fatty acyl CoA→formyl-CoA + an odd numbered straight chain 2,3,4-saturated fatty aldehyde (EC 4.1.2.63)
No genes
Formyl-CoA hydrolase:
formyl-CoA + H2O→formate + coenzyme A + H+
(EC 3.1.2.10)
No genes
Aldehyde dehydrogenase (NAD(+)):
an odd numbered straight chain 2,3,4-saturated fatty aldehyde + NAD+ + H2O→an odd numbered straight chain 2,3,4-saturated fatty acid + NADH + 2 H+
(EC 1.2.1.3)
BPHYT_RS00120
BPHYT_RS00395
BPHYT_RS05370
BPHYT_RS07490
BPHYT_RS09900
BPHYT_RS17340
BPHYT_RS18745
BPHYT_RS19710
BPHYT_RS20795
BPHYT_RS25705
BPHYT_RS25810
BPHYT_RS27405
BPHYT_RS28770
BPHYT_RS29875
BPHYT_RS30510
BPHYT_RS32650
BPHYT_RS34980
BPHYT_RS35600
Long-chain-fatty-acid--CoA ligase:
an odd numbered straight chain 2,3,4-saturated fatty acid + ATP + coenzyme A→an odd numbered straight chain 2,3,4-saturated fatty acyl CoA + AMP + diphosphate
(EC 6.2.1.3)
BPHYT_RS08270
BPHYT_RS17295
BPHYT_RS19375

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information