MetaCyc Pathway: 2-allylmalonyl-CoA biosynthesis in Burkholderia phytofirmans PsJN

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propanoyl-CoA + TcsB polyketide synthase→propanoyl-[TcsB polyketide synthase] + coenzyme A
No genes
malonyl-CoA + TcsA polyketide synthase→malonyl-[TcsA polyketide synthase] + coenzyme A
No genes
malonyl-[TcsA polyketide synthase] + propanoyl-[TcsB polyketide synthase] + H+→3-oxopentanoyl-[TcsA polyketide synthase] + CO2 + TcsB polyketide synthase
No genes
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
3-oxopentanoyl-[TcsA polyketide synthase] + NADPH + H+→(3R)-3-hydroxypentanoyl-[TcsA polyketide synthase] + NADP+ (EC 1.1.1.100)
BPHYT_RS01050
BPHYT_RS04770
BPHYT_RS05365
BPHYT_RS05385
BPHYT_RS06420
BPHYT_RS07065
BPHYT_RS08285
BPHYT_RS08365
BPHYT_RS08890
BPHYT_RS10170
BPHYT_RS10200
BPHYT_RS10595
BPHYT_RS10630
BPHYT_RS10735
BPHYT_RS11845
BPHYT_RS13055
BPHYT_RS14425
BPHYT_RS15135
BPHYT_RS15890
BPHYT_RS16040
BPHYT_RS16940
BPHYT_RS20510
BPHYT_RS20625
BPHYT_RS20775
BPHYT_RS21600
BPHYT_RS22135
BPHYT_RS25030
BPHYT_RS25415
BPHYT_RS25655
BPHYT_RS26470
BPHYT_RS28250
BPHYT_RS30440
BPHYT_RS30465
BPHYT_RS30795
BPHYT_RS31385
BPHYT_RS31405
BPHYT_RS31610
BPHYT_RS31900
BPHYT_RS33140
BPHYT_RS33705
BPHYT_RS34945
BPHYT_RS34965
BPHYT_RS35505
BPHYT_RS35675
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
(3R)-3-hydroxypentanoyl-[TcsA polyketide synthase]→(2E)-pent-2-enoyl-[TcsA polyketide synthase] + H2O (EC 4.2.1.59)
BPHYT_RS12085
(2E)-pent-2-enoyl-[TcsA polyketide synthase] + CO2 + NADPH→2-carboxypentanoyl-[TcsA polyketide synthase] + NADP+
No genes
2-carboxypentanoyl-[TcsA polyketide synthase] + FAD + H+→2-allylmalonyl-[TcsA polyketide synthase] + FADH2
No genes
2-allylmalonyl-[TcsA polyketide synthase] + coenzyme A→2-allylmalonyl-CoA + TcsA polyketide synthase
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information