MetaCyc Pathway: aromatic biogenic amine degradation (bacteria) in Burkholderia phytofirmans PsJN

Add experiment(s):


Octopamine dehydratase:
octopamine→(4-hydroxyphenyl)acetaldehyde + ammonium (EC 4.2.1.87)
No genes
tyramine + an oxidized electron carrier + H2O→(4-hydroxyphenyl)acetaldehyde + ammonium + a reduced two electron carrier
No genes
Monoamine oxidase:
tyramine + dioxygen + H2O→(4-hydroxyphenyl)acetaldehyde + ammonium + hydrogen peroxide (EC 1.4.3.4)
BPHYT_RS09910
BPHYT_RS31410
Monoamine oxidase:
dopamine + dioxygen + H2O→3,4-dihydroxyphenylacetaldehyde + ammonium + hydrogen peroxide (EC 1.4.3.4)
BPHYT_RS31410
Synephrine dehydratase:
(R)-synephrine→(4-hydroxyphenyl)acetaldehyde + methylamine (EC 4.2.1.88)
No genes
4-hydroxyphenylacetaldehyde dehydrogenase:
(4-hydroxyphenyl)acetaldehyde + NAD+ + H2O→(4-hydroxyphenyl)acetate + NADH + 2 H+ (EC 1.2.1.53)
No genes
Aldehyde dehydrogenase (NAD(+)):
3,4-dihydroxyphenylacetaldehyde + NAD+ + H2O→(3,4-dihydroxyphenyl)acetate + NADH + 2 H+ (EC 1.2.1.3)
BPHYT_RS00120
BPHYT_RS00395
BPHYT_RS05370
BPHYT_RS07490
BPHYT_RS09900
BPHYT_RS17340
BPHYT_RS18745
BPHYT_RS19710
BPHYT_RS20795
BPHYT_RS25705
BPHYT_RS25810
BPHYT_RS27405
BPHYT_RS28770
BPHYT_RS29875
BPHYT_RS30510
BPHYT_RS32650
BPHYT_RS34980
BPHYT_RS35600
(4-hydroxyphenyl)acetate + FADH2 + dioxygen→(3,4-dihydroxyphenyl)acetate + FAD + H+ + H2O (EC 1.14.14.9)
BPHYT_RS10745
BPHYT_RS30300

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information