MetaCyc Pathway: pyruvate fermentation to butanol I in Burkholderia phytofirmans PsJN

Add experiment(s):


Pyruvate synthase:
pyruvate + coenzyme A + 2 an oxidized ferredoxin [iron-sulfur] cluster→acetyl-CoA + CO2 + H+ + 2 a reduced ferredoxin [iron-sulfur] cluster (EC 1.2.7.1)
No genes
Acetyl-CoA C-acyltransferase:
2 acetyl-CoA→acetoacetyl-CoA + coenzyme A (EC 2.3.1.16; 2.3.1.9)
BPHYT_RS02230
BPHYT_RS03230
BPHYT_RS08275
BPHYT_RS09150
BPHYT_RS09180
BPHYT_RS09565
BPHYT_RS17345
BPHYT_RS21955
BPHYT_RS29385
3-hydroxyacyl-CoA dehydrogenase (in reverse):
acetoacetyl-CoA + NADH + H+→(S)-3-hydroxybutanoyl-CoA + NAD+ (EC 1.1.1.35)
BPHYT_RS03225
BPHYT_RS06760
BPHYT_RS09560
BPHYT_RS13545
BPHYT_RS28020
BPHYT_RS34155
(S)-3-hydroxybutanoyl-CoA→crotonyl-CoA + H2O (EC 4.2.1.150)
BPHYT_RS02345
BPHYT_RS03225
BPHYT_RS03235
BPHYT_RS03825
BPHYT_RS08375
BPHYT_RS08630
BPHYT_RS09560
BPHYT_RS10815
BPHYT_RS11780
BPHYT_RS13545
BPHYT_RS14830
BPHYT_RS25360
BPHYT_RS25695
BPHYT_RS27105
BPHYT_RS27895
BPHYT_RS28620
BPHYT_RS35465
crotonyl-CoA[cytosol] + 2 NADH[cytosol] + 2 an oxidized ferredoxin [iron-sulfur] cluster[cytosol]→butanoyl-CoA[cytosol] + 2 NAD+[cytosol] + 2 a reduced ferredoxin [iron-sulfur] cluster[cytosol] (EC 1.3.1.109)
No genes
Butanal dehydrogenase (in reverse):
butanoyl-CoA + NAD(P)H + H+→1-butanal + coenzyme A + NAD(P)+ (EC 1.2.1.57)
No genes
Alcohol dehydrogenase (NADP(+)) (in reverse):
1-butanal + NADPH + H+→butan-1-ol + NADP+ (EC 1.1.1.2)
BPHYT_RS07065
1-butanal + NADH + H+→butan-1-ol + NAD+
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information